Gene: Gjb3

Order

Name gap junction protein, beta 3

Synonyms
  • Gjb-3
  • Cx31
  • connexin 31
  • Cnx31
  • D4Wsu144e

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:95721    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Gjb3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Gjb3 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
enlarged heart Gjb3tm1.1(KOMP)Vlcg HET Male postnatal 0.0
prenatal lethality prior to heart atrial septation Gjb3tm1.1(KOMP)Vlcg HOM Female Male embryonic day 14.5 0.0
preweaning lethality, complete penetrance Gjb3tm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
decreased basophil cell number Gjb3tm1.1(KOMP)Vlcg HET Female Male postnatal 4.25E-6
increased or absent threshold for auditory brainstem response Gjb3tm1.1(KOMP)Vlcg HET Female Male postnatal 3.99E-5
decreased eosinophil cell number Gjb3tm1.1(KOMP)Vlcg HET Female Male postnatal 7.61E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Blood 2 No
Bone marrow 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cecum 2 No (12/383)
Cerebellum 2 No
Cerebral cortex 2 No
Chest bone 2 No
Colon 2 No (12/127) (1/2)
Diaphragm 2 No
Duodenum 2 No (2/127)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No (2/2)
Gall bladder 2 No
Gonadal fat pad 2 No
Harderian gland 2 No
Heart 2 No
Hindlimb 2 No
Hippocampus 2 No
Hypothalamus 2 No
Ileum 2 No (14/127)
Jejunum 2 No (6/127)
Kidney 2 No (18/584) (1/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No (1/2)
Mesenteric lymph node 2 No
Mesenteric adipose tissue 2 No
Midbrain 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Parotid gland 2 No
Penis 2 No (1/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584) (1/2)
Quadriceps 2 No
Sciatic nerve 2 No
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Stomach pyloric region 2 No
Striatum 2 No
Sublingual gland 2 No
Submandibular gland 2 No (2/132)
Testis 2 No (2/584)
Thymus 2 No
Thyroid gland 2 No (15/584)
Tongue 2 No (5/127) (2/2)
Trachea 2 No (2/2)
Trigeminal V nerve 2 No
Urinary bladder 2 No (2/2)
Uterus 2 No
Vagina 2 No (1/2)
Vas deferens 2 No (15/388) (1/2)
Vascular system 2 No
Vesicular gland 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system digestive system sensory organ reproductive system exocrine system integumental system trunk urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 3 (1/47)
Axial skeleton 3 (1/51) (4/5)
Brain 3 (6/485) (1/5)
Central nervous system ganglion 3 (1/51)
Dorsal root ganglion 3 (1/47)
Ear 3 (1/485) (5/5)
Embryo 3 (1/485) (5/5)
Outer ear 2 (1/47)
Eye 3 (1/485)
Foot 3 (1/485) (5/5)
Forebrain 3 (1/485)
Forelimb 3 (1/485) (5/5)
Fronto-nasal process 3 (1/48) (5/5)
Hand 3 (1/485) (5/5)
Head 3 (5/485)
Head mesenchyme 3 (1/47)
Heart 3 (1/485) (4/5)
Heart ventricle 3 (1/47)
Hindbrain 3 (6/485)
Hindlimb 3 (1/485) (5/5)
Inner ear 3 (1/46) (5/5)
Liver 3 (1/485)
Lung 3 (1/485)
Mandibular process 3 (1/485)
Maxillary process 3 (1/485)
Meckel's cartilage 3
Metanephros 3 (1/46) (5/5)
Midbrain 3 (1/485)
Nasal septum 3 (1/47)
Nose 3 (1/51) (5/5)
Notochord 3 (1/47)
Oral cavity 3 (1/485) (3/5)
Outflow tract 3 (1/47)
Pericardium 3 (1/46) (3/5)
Pharynx 1 (1/46)
Skeleton 3 (1/51) (5/5)
Skin 3 (1/485)
Spinal cord 3 (1/50)
Tail 3 (1/485)
Tail somite 3 (1/485)
Tongue 3 (1/46) (3/5)
Trunk mesenchyme 3 (1/47)
Vibrissa 3 (1/47) (1/5)


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    12 Images
  • X-ray: XRay Images Lateral Orientation
    12 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Gjb3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Gjb3tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Fixed Tissue
Gjb3tm214962(L1L2_Bact_P)
Vector
Gene