Gene: Ercc3

Order

Name excision repair cross-complementing rodent repair deficiency, complementation group 3

Synonyms XPB

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:95414    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Ercc3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ercc3 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
embryonic lethality prior to organogenesis Ercc3tm1b(NCOM)Mfgc HOM Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Ercc3tm1b(NCOM)Mfgc HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Ercc3tm1b(NCOM)Mfgc HOM Female Male n/a 0.0
increased circulating potassium level Ercc3tm1b(NCOM)Mfgc HET Male postnatal 1.72E-7

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
No expression data was found for this adult tab
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 6 (6/482) Image Only
Ear 6 (1/482) Image Only
Embryo 6 (1/482) (6/6)
Eye 6 (1/482) Image Only
Foot 6 (1/482) Image Only
Forebrain 6 (1/482) Image Only
Forelimb 6 (1/482) Image Only
Hand 6 (1/482) Image Only
Head 6 (5/482) Image Only
Heart 6 (1/482) Image Only
Hindbrain 6 (6/482) Image Only
Hindlimb 6 (1/482) Image Only
Liver 6 (1/482) Image Only
Lung 6 (1/482) Image Only
Mandibular process 6 (1/482) Image Only
Maxillary process 6 (1/482) Image Only
Midbrain 6 (1/482) Image Only
Oral cavity 6 (1/482) Image Only
Skin 6 (1/482) Image Only
Tail 6 (1/482) Image Only
Tail somite 6 (1/482) Image Only


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Gross Pathology and Tissue Collection
    8 Images
  • Eye Morphology: Images Ophthalmoscopy
    5 Images
  • Histopathology
    3 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Embryo LacZ: LacZ images wholemount
    24 Images
  • Eye Morphology: Images Slit Lamp
    1 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ercc3tm1a(NCOM)Mfgc KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Ercc3tm1b(NCOM)Mfgc Reporter-tagged deletion allele (post-Cre)
Vector
Gene