Gene: Edn2

Order

Name endothelin 2

Synonyms
  • vasoactive intestinal contractor peptide
  • VIC

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:95284    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Edn2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Edn2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Edn2tm1b(KOMP)Mbp HOM Female Male n/a 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No (2/415)
Aorta 4 No
Bone 4 No
Brain 4 No
Brainstem 4 No
Brown adipose tissue 4 No
Cartilage tissue 4 No
Cecum 4 No (12/383)
Cerebellum 4 No
Cerebral cortex 4 No
Chest bone 4 No
Colon 4 No (12/127) (4/4)
Cranium 4 No
Diaphragm 4 No
Duodenum 4 No (2/127) (4/4)
Epididymis 4 No (18/134)
Esophagus 4 No (7/415)
Eye 4 No
Gall bladder 4 No
Gonadal fat pad 4 No
Harderian gland 4 No
Heart 4 No
Hindlimb 4 No
Hippocampus 4 No
Hypothalamus 4 No
Ileum 4 No (14/127) (4/4)
Jejunum 4 No (6/127)
Kidney 4 No (18/584)
Large intestine 4 No (10/584) (4/4)
Liver 4 No
Lower urinary tract 4 No
Lung 4 No
Lymph node 4 No
Main olfactory bulb 4 No
Mammary gland 4 No
Mesenteric lymph node 4 No
Mesenteric adipose tissue 4 No
Midbrain 4 No
Olfactory lobe 4 No
Oral epithelium 4 No
Ovary 4 No (1/584)
Oviduct 4 No
Pancreas 4 No (5/584)
Parathyroid gland 4 No
Parotid gland 4 No
Penis 4 No
Peripheral nervous system 4 No
Peyer's patch 4 No (4/4)
Pituitary gland 4 No
Prostate gland 4 No (12/584)
Quadriceps 4 No
Sciatic nerve 4 No
Skeletal muscle 4 No
Skin 4 No (4/4)
Small intestine 4 No (9/584) (4/4)
Spinal cord 4 No
Spleen 4 No (2/584)
Stomach 4 No (12/584)
Stomach pyloric region 4 No
Striatum 4 No
Sublingual gland 4 No
Submandibular gland 4 No (2/132)
Testis 4 No (2/584) (2/4)
Thalamus 4 No
Thymus 4 No
Thyroid gland 4 No (15/584)
Tongue 4 No (5/127)
Trachea 4 No
Trigeminal V nerve 4 No
Urinary bladder 4 No
Uterus 4 No
Vagina 4 No
Vas deferens 4 No (15/388)
Vascular system 4 No
Vesicular gland 4 No
White adipose tissue 4 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    digestive system
    reproductive system
    immune system
    integumental system
    trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 3 (6/485)
Ear 3 (1/485)
Embryo 3 (1/485)
Eye 3 (1/485)
Foot 3 (1/485)
Forearm 3 (1/282)
Forebrain 3 (1/485)
Forelimb 3 (1/485)
Hand 3 (1/485)
Head 3 (5/485)
Heart 3 (1/485)
Hindbrain 3 (6/485)
Hindlimb 3 (1/485)
Liver 3 (1/485)
Lower leg 3 (1/282)
Lung 3 (1/485)
Mandibular process 3 (1/485)
Maxillary process 3 (1/485)
Midbrain 3 (1/485)
Oral cavity 3 (1/485)
Skin 3 (1/485)
Tail 3 (1/485)
Tail somite 3 (1/485)
Upper arm 3 (1/282)
Upper leg 3 (1/282)


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Eye Morphology: Images Ophthalmoscopy
    5 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • Adult LacZ: LacZ Images Wholemount
    102 Images
  • Embryo LacZ: LacZ images wholemount
    6 Images
  • Eye Morphology: Images Slit Lamp
    1 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Edn2tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Edn2tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene