Gene: Cdh1

Order

Name cadherin 1

Synonyms
  • UM
  • E-cad
  • E-cadherin
  • Ecad
  • L-CAM
  • uvomorulin

Status ES CellsMice
tm1a
phenotype data available

Links MGI:88354    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Cdh1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Cdh1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Cdh1tm1a(EUCOMM)Wtsi HOM Female Male n/a 0.0
increased body weight Cdh1tm1a(EUCOMM)Wtsi HET Female Male postnatal 3.03E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No (1/562)
Blood vessel 2 No
Bone 2 No (1/539)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562) (2/2)
Gall bladder 2 No (2/2)
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (3/562) (2/2)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562)
Mammary gland 2 No (1/2)
Esophagus 2 No (2/2)
Olfactory lobe 2 No
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (2/2)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562) (1/2)
Skeletal muscle tissue 2 No
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562) (2/2)
Uterus 2 No (2/562) (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system endocrine system digestive system nervous system sensory organ reproductive system immune system exocrine system integumental system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (23)
  • Cdh1tm1a(EUCOMM)Wtsi
    pituitary gland, peripheral nervous system, HET, Female, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    skin, HET, Female, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    kidney, HET, Female, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    small intestine, HET, Female, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    peripheral nervous system, HET, Female, WTSI

show all 23 images

trunk (14)
  • Cdh1tm1a(EUCOMM)Wtsi
    kidney, HET, Female, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    small intestine, HET, Female, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    prostate gland, HET, Male, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    gall bladder, liver, HET, Female, WTSI

show all 14 images

nervous system (5)
  • Cdh1tm1a(EUCOMM)Wtsi
    pituitary gland, peripheral nervous system, HET, Female, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    peripheral nervous system, HET, Female, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    brain, HET, Female, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    brain, HET, Female, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    spinal cord, HET, Female, WTSI
digestive system (4)
  • Cdh1tm1a(EUCOMM)Wtsi
    small intestine, HET, Female, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    gall bladder, liver, HET, Female, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    oesophagus, HET, Female, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    large intestine, HET, Female, WTSI
integumental system (3)
  • Cdh1tm1a(EUCOMM)Wtsi
    skin, HET, Female, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    pinna, skin, HET, Female, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    mammary gland, HET, Female, WTSI
reproductive system (3)
  • Cdh1tm1a(EUCOMM)Wtsi
    prostate gland, HET, Male, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    ovary, HET, Female, WTSI
exocrine system (2)
  • Cdh1tm1a(EUCOMM)Wtsi
    prostate gland, HET, Male, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    mammary gland, HET, Female, WTSI
respiratory system (2)
  • Cdh1tm1a(EUCOMM)Wtsi
    lung, HET, Female, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    trachea, thyroid gland, HET, Female, WTSI
sensory organ (2)
  • Cdh1tm1a(EUCOMM)Wtsi
    pinna, skin, HET, Female, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    eye, HET, Female, WTSI
urinary system (2)
  • Cdh1tm1a(EUCOMM)Wtsi
    kidney, HET, Female, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
endocrine system (1)
  • Cdh1tm1a(EUCOMM)Wtsi
    trachea, thyroid gland, HET, Female, WTSI
immune system (1)
  • Cdh1tm1a(EUCOMM)Wtsi
    thymus, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (153)
  • Cdh1tm1a(EUCOMM)Wtsi
    head, WT, Male, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    WT, Male, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    body, WT, Male, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    WT, Male, WTSI
  • Cdh1tm1a(EUCOMM)Wtsi
    head, WT, Male, WTSI

show all 153 images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Cdh1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene