Gene: Bmi1

Order

Name Bmi1 polycomb ring finger oncogene

Synonyms
  • Bmi1
  • Pcgf4
  • Bmi-1

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:88174    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Bmi1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Bmi1 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal craniofacial morphology Bmi1tm1.1(KOMP)Vlcg HET Female embryonic day 15.5 0.0
abnormal embryo size Bmi1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
abnormal embryo size Bmi1tm1.1(KOMP)Vlcg HET Female embryonic day 15.5 0.0
anophthalmia Bmi1tm1.1(KOMP)Vlcg HET Female embryonic day 15.5 0.0
edema Bmi1tm1.1(KOMP)Vlcg HET Female Male embryonic day 15.5 0.0
edema Bmi1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
microphthalmia Bmi1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
microphthalmia Bmi1tm1.1(KOMP)Vlcg HET Female Male embryonic day 15.5 0.0
prenatal lethality prior to heart atrial septation Bmi1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 14.5 0.0
preweaning lethality, incomplete penetrance Bmi1tm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
decreased vertical activity Bmi1tm1.1(KOMP)Vlcg HET Male postnatal 4.36E-6
impaired glucose tolerance Bmi1tm1.1(KOMP)Vlcg HET Male postnatal 9.75E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
No expression data was found for this adult tab
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 4 (6/482) Image Only
Ear 4 (1/482) Image Only
Embryo 4 (1/482) Image Only
Eye 4 (1/482) Image Only
Foot 4 (1/482) Image Only
Forebrain 4 (1/482) Image Only
Forelimb 4 (1/482) Image Only
Hand 4 (1/482) Image Only
Head 4 (5/482) Image Only
Heart 4 (1/482) Image Only
Hindbrain 4 (6/482) Image Only
Hindlimb 4 (1/482) Image Only
Liver 4 (1/482) Image Only
Lung 4 (1/482) Image Only
Mandibular process 4 (1/482) Image Only
Maxillary process 4 (1/482) Image Only
Midbrain 4 (1/482) Image Only
Oral cavity 4 (1/482) Image Only
Skin 4 (1/482) Image Only
Tail 4 (1/482) Image Only
Tail somite 4 (1/482) Image Only


Associated Images

Associated Images
  • Embryo LacZ: LacZ images wholemount
    24 Images
  • Gross Morphology Embryo E14.5-E15.5
    4 Images
  • X-ray: XRay Images Lateral Orientation
    11 Images
  • X-ray: XRay Images Dorso Ventral
    9 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Bmi1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Bmi1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Fixed Tissue
Paraffin-embedded Sections
Bmi1tm297191(L1L2_Bact_P)
Vector
Gene