Gene: Ace

Order

Name angiotensin I converting enzyme (peptidyl-dipeptidase A) 1

Synonyms CD143

Status ES CellsMice
tm1.1
Mice
tm1
phenotype data available

Links MGI:87874    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Ace

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ace data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Acetm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal embryo size Acetm1.1(KOMP)Vlcg HET Female Male embryonic day 9.5 0.0
abnormal seminal vesicle morphology Acetm1.1(KOMP)Vlcg HET Male postnatal 0.0
embryonic growth retardation Acetm1.1(KOMP)Vlcg HET Female Male embryonic day 9.5 0.0
embryonic growth retardation Acetm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Acetm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Acetm1.1(KOMP)Vlcg HOM Female Male n/a 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (1/2)
Aorta 2 No
Blood 2 No
Bone marrow 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No
Cecum 2 No (12/383) (2/2)
Cerebellum 2 No
Cerebral cortex 2 No
Chest bone 2 No
Colon 2 No (12/127) (2/2)
Diaphragm 2 No
Duodenum 2 No (2/127) (1/2)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415)
Eye 2 No
Gall bladder 2 No
Gonadal fat pad 2 No
Harderian gland 2 No (1/2)
Heart 2 No
Hindlimb 2 No
Hippocampus 2 No
Hypothalamus 2 No
Ileum 2 No (14/127) (2/2)
Jejunum 2 No (6/127) (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No (1/2)
Lymph node 2 No
Mammary gland 2 No
Mesenteric lymph node 2 No (2/2)
Mesenteric adipose tissue 2 No
Midbrain 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584) (2/2)
Parathyroid gland 2 No
Parotid gland 2 No (1/2)
Penis 2 No
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584) (1/2)
Quadriceps 2 No (1/2)
Sciatic nerve 2 No
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Stomach pyloric region 2 No
Striatum 2 No
Sublingual gland 2 No (1/2)
Submandibular gland 2 No (2/132) (2/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584)
Tongue 2 No (5/127) (2/2)
Trachea 2 No
Trigeminal V nerve 2 No
Urinary bladder 2 No
Uterus 2 No
Vagina 2 No (1/2)
Vas deferens 2 No (15/388) (1/2)
Vascular system 2 No
Vesicular gland 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    respiratory system endocrine system digestive system set of connective tissues reproductive system adipose tissue musculoskeletal system trunk postnatal mouse sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Acetm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Fixed Tissue
Acetm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Acetm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene