Gene: Cyp3a59

Order

Name cytochrome P450, family 3, subfamily a, polypeptide 59

Status ES CellsMice
em1

Links MGI:3769707    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Cyp3a59

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Cyp3a59 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Cyp3a59em1(IMPC)Marc HOM Female Male n/a 0.0
decreased mean platelet volume Cyp3a59em1(IMPC)Marc HET Female Male postnatal 2.58E-9
thrombocytopenia Cyp3a59em1(IMPC)Marc HET Female Male postnatal 1.43E-8

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Expression

Expression data not available

Associated Images

Phenotype associated images not available

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Cyp3a59em1(IMPC)Marc Indel causing a Frameshift Mutation
Vector
Gene
Cyp3a59tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene