Gene: Aars2

Order

Name alanyl-tRNA synthetase 2, mitochondrial

Synonyms Aarsl

Status ES CellsMice
tm1
phenotype data available

Links MGI:2681839    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Aars2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Aars2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Aars2tm1(KOMP)Wtsi HOM Female Male n/a 0.0
increased basophil cell number Aars2tm1(KOMP)Wtsi HET Female Male postnatal 8.48E-8
decreased red blood cell distribution width Aars2tm1(KOMP)Wtsi HET Female Male postnatal 5.44E-7
abnormal heart left ventricle morphology Aars2tm1(KOMP)Wtsi HET Female postnatal 2.24E-5
impaired pupillary reflex Aars2tm1(KOMP)Wtsi HET Female postnatal 7.74E-5

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Expression

Expression data not available

Associated Images

Phenotype associated images not available

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Aars2tm1(KOMP)Wtsi Reporter-tagged deletion allele (with selection cassette)
Vector
Gene