Gene: Dcun1d3

Order

Name DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)

Synonyms 1700020A13Rik

Status ES CellsMice
em1
phenotype data available

Links MGI:2679003    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Dcun1d3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Dcun1d3 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Dcun1d3em1(IMPC)Wtsi HOM Female Male n/a 0.0
decreased fasted circulating glucose level Dcun1d3em1(IMPC)Wtsi HOM Female Male postnatal 1.81E-10
decreased circulating glucose level Dcun1d3em1(IMPC)Wtsi HOM Female Male postnatal 1.47E-8
decreased circulating free fatty acid level Dcun1d3em1(IMPC)Wtsi HOM Female Male postnatal 9.16E-7
decreased bone mineral density Dcun1d3em1(IMPC)Wtsi HOM Female postnatal 3.25E-5
increased bone mineral density Dcun1d3em1(IMPC)Wtsi HOM Male postnatal 3.25E-5
thrombocytopenia Dcun1d3em1(IMPC)Wtsi HOM Female Male postnatal 3.42E-5
increased lean body mass Dcun1d3em1(IMPC)Wtsi HOM Female Male postnatal 8.49E-5
decreased total body fat amount Dcun1d3em1(IMPC)Wtsi HOM Female Male postnatal 9.54E-5

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Associated Images
  • DSS Histology
    8 Images
Legacy Phenotype Associated Images
Dysmorphology (5)
  • Dcun1d3em1(IMPC)Wtsi
    narrow eye opening, eye, abnormal eye morphology, HOM, Female, WTSI
  • Dcun1d3em1(IMPC)Wtsi
    head, abnormal snout morphology, asymmetric snout, snout, HOM, Male, WTSI
  • Dcun1d3em1(IMPC)Wtsi
    head, abnormal snout morphology, asymmetric snout, HOM, Female, WTSI
  • Dcun1d3em1(IMPC)Wtsi
    head, snout, abnormal snout morphology, short snout, HOM, Male, WTSI
  • Dcun1d3em1(IMPC)Wtsi
    head, snout, abnormal snout morphology, asymmetric snout, HOM, Male, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Dcun1d3em1(IMPC)Wtsi Exdel
Vector
Gene
Dcun1d3tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene