Gene: Ccdc114

Order

Name coiled-coil domain containing 114

Status ES CellsMice
tm2b
phenotype data available

Links MGI:2446120    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Ccdc114

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ccdc114 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Ccdc114tm2b(EUCOMM)Wtsi HOM Female Male n/a 0.0
hyperactivity Ccdc114tm2b(EUCOMM)Wtsi HET Female Male postnatal 2.92E-8
abnormal behavior Ccdc114tm2b(EUCOMM)Wtsi HET Female Male postnatal 1.88E-7
increased cardiac muscle contractility Ccdc114tm2b(EUCOMM)Wtsi HET Male postnatal 4.88E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cecum 2 No (12/383)
Cerebellum 2 No
Cerebral cortex 2 No
Esophagus 2 No (7/415)
Eye 2 No
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No
Mesenteric lymph node 2 No
Olfactory lobe 2 No
Oral epithelium 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Parathyroid gland 2 No (2/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No (2/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Trigeminal V nerve 2 No
Urinary bladder 2 No
Uterus 2 No
Vas deferens 2 No (15/388)
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system endocrine system nervous system reproductive system trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2 (1/47)
Axial skeleton 2 (1/51)
Brain 2 (6/485) (2/2)
Central nervous system ganglion 2 (1/51) (2/2)
Cranium 2 (1/46) (2/2)
Dorsal root ganglion 2 (1/47)
Ear 2 (1/485)
Embryo 2 (1/485) (2/2)
Outer ear 2 (1/47)
Eye 2 (1/485)
Femur pre-cartilage condensation 2 (1/46)
Foot 2 (1/485)
Forearm 2 (1/282)
Forebrain 2 (1/485) (2/2)
Forelimb 2 (1/485)
Fronto-nasal process 2 (1/48)
Gut 2 (1/50) (2/2)
Hand 2 (1/485)
Head 2 (5/485) (2/2)
Head mesenchyme 2 (1/47)
Heart 2 (1/485)
Heart ventricle 2 (1/47)
Hindbrain 2 (6/485) (2/2)
Hindlimb 2 (1/485)
Humerus pre-cartilage condensation 2 (1/46)
Inner ear 2 (1/46)
Intestine 2 (1/47)
Liver 2 (1/485)
Lower leg 2 (1/282)
Lung 2 (1/485)
Mandibular process 2 (1/485)
Maxillary process 2 (1/485)
Mesonephros of female 2 (1/46)
Mesonephros of male 2 (1/46)
Metanephros 2 (1/46)
Midbrain 2 (1/485) (2/2)
Nasal septum 2 (1/47)
Nose 2 (1/51)
Notochord 2 (1/47) (2/2)
Oral cavity 2 (1/485)
Outflow tract 2 (1/47)
Pancreas 2 (1/46)
Pericardium 2 (1/46)
Pharynx 2 (1/46)
Radius-ulna pre-cartilage condensation 2 (1/46)
Rib pre-cartilage condensation 2 (1/46)
Skeleton 2 (1/51)
Skin 2 (1/485)
Spinal cord 2 (1/50) (2/2)
Stomach 2 (1/46)
Tail 2 (1/485) (2/2)
Tail somite 2 (1/485)
Thoracic vertebral cartilage condensation 2 (1/46)
Tongue 2 (1/46)
Trachea 2 (1/50)
Trunk mesenchyme 2 (1/47)
Umbilical artery embryonic part 2 (1/47)
Umbilical vein embryonic part 2 (1/47)
Upper arm 2 (1/282)
Upper leg 2 (1/282)
Urinary system 2 (1/50)
Vibrissa 2 (1/47)


Associated Images

Phenotype associated images not available

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ccdc114tm2b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Ccdc114tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Ccdc114tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene