Gene: Caskin1

Order

Name CASK interacting protein 1

Synonyms
  • 3300002N10Rik
  • C630036E02Rik

Status ES CellsMice
tm1a
Mice
tm1b
Mice
em1
phenotype data available

Links MGI:2442952    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable     Homozygous - Subviable

Phenotype associations for Caskin1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Caskin1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal epididymis morphology Caskin1tm1b(KOMP)Wtsi HET Male postnatal 0.0
abnormal seminal vesicle morphology Caskin1tm1b(KOMP)Wtsi HET Male postnatal 0.0
cystolithiasis Caskin1tm1b(KOMP)Wtsi HET Male postnatal 0.0
preweaning lethality, incomplete penetrance Caskin1tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
decreased bone mineral content Caskin1em1(IMPC)Mbp HOM Female Male postnatal 6.6E-12
decreased lean body mass Caskin1em1(IMPC)Mbp HOM Female Male postnatal 2.49E-11
abnormal bone structure Caskin1em1(IMPC)Mbp HOM Female Male postnatal 4.21E-11
decreased prepulse inhibition Caskin1em1(IMPC)Mbp HOM Female Male postnatal 5.6E-9
decreased bone mineral density Caskin1em1(IMPC)Mbp HOM Female Male postnatal 1.12E-8
abnormal coat/hair pigmentation Caskin1tm1b(KOMP)Wtsi HET Female postnatal 5.88E-8
decreased circulating insulin level Caskin1tm1b(KOMP)Wtsi HET Male postnatal 7.37E-7
impaired glucose tolerance Caskin1em1(IMPC)Mbp HOM Female postnatal 7.24E-5
improved glucose tolerance Caskin1em1(IMPC)Mbp HOM Male postnatal 7.24E-5
increased respiratory quotient Caskin1tm1b(KOMP)Wtsi HET Male postnatal 9.92E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (2/2)
Aorta 2 No (1/562)
Bone 1 No (1/539) (1/1)
Bone marrow 1 No
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (1/2)
Esophagus 2 No (2/393)
Eye 2 No (1/562) (1/2)
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Olfactory lobe 2 No (4/393) (1/2)
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562)
Stomach 2 No (9/562) (1/2)
Striatum 2 No (4/562)
Testis 2 No (4/562)
Thymus 2 No
Thyroid gland 2 No (16/562) (1/2)
Trachea 2 No (3/562)
Urinary bladder 1 No (1/1)
Uterus 2 No (2/562)
Vascular system 2 No (1/393)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    postnatal mouse
    digestive system
    nervous system
    sensory organ
    musculoskeletal system
    trunk
    urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • Adult LacZ: LacZ Images Section
    14 Images
  • X-ray: XRay Images Lateral Orientation
    23 Images
  • X-ray: XRay Images Dorso Ventral
    17 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Caskin1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Caskin1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Caskin1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Fixed Tissue
Paraffin-embedded Sections
Caskin1em1(IMPC)Mbp Inter-exdel deletion
Vector
Gene
Fixed Tissue
Paraffin-embedded Sections