Gene: Ggnbp2

Order

Name gametogenetin binding protein 2

Synonyms
  • DIF-3
  • Zfp403
  • D330017P12Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:2387356    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Ggnbp2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ggnbp2 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
Epididymis - depletion Ggnbp2tm1b(KOMP)Wtsi HOM Male postnatal 0.0
Testes - process of degenerative change Ggnbp2tm1b(KOMP)Wtsi HOM Male postnatal 0.0
abnormal embryo size Ggnbp2tm1b(KOMP)Wtsi HET Female embryonic day 15.5 0.0
abnormal embryo size Ggnbp2tm1b(KOMP)Wtsi HOM Female embryonic day 15.5 0.0
anophthalmia Ggnbp2tm1b(KOMP)Wtsi HET Female Male embryonic day 15.5 0.0
anophthalmia Ggnbp2tm1b(KOMP)Wtsi HOM Female embryonic day 15.5 0.0
edema Ggnbp2tm1b(KOMP)Wtsi HET Female Male embryonic day 15.5 0.0
edema Ggnbp2tm1b(KOMP)Wtsi HOM Female Male embryonic day 15.5 0.0
prenatal lethality prior to heart atrial septation Ggnbp2tm1b(KOMP)Wtsi HOM Female Male embryonic day 14.5 0.0
preweaning lethality, incomplete penetrance Ggnbp2tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
abnormal behavior Ggnbp2tm1b(KOMP)Wtsi HET Female postnatal 2.78E-9
decreased circulating total protein level Ggnbp2tm1b(KOMP)Wtsi HET Female Male postnatal 2.49E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
No expression data was found for this adult tab
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2 (1/51) (2/2)
Brain 3 (6/485) (2/4)
Central nervous system ganglion 2 (1/51) (2/2)
Ear 3 (1/485) (2/4)
Embryo 3 (1/485) (2/4)
Eye 3 (1/485) (2/4)
Foot 3 (1/485)
Forebrain 3 (1/485) (2/4)
Forelimb 3 (1/485) (2/4)
Gut 2 (1/50) (2/2)
Hand 3 (1/485)
Head 3 (5/485) (2/4)
Heart 3 (1/485) (2/4)
Hindbrain 3 (6/485) (2/4)
Hindlimb 3 (1/485) (2/4)
Liver 3 (1/485) (2/4)
Lung 3 (1/485) (2/4)
Mandibular process 3 (1/485) (2/4)
Maxillary process 3 (1/485) (2/4)
Midbrain 3 (1/485) (2/4)
Nose 2 (1/51) (2/2)
Oral cavity 3 (1/485) (2/4)
Skeleton 2 (1/51) (2/2)
Skin 3 (1/485) (2/4)
Spinal cord 2 (1/50) (2/2)
Tail 3 (1/485) (2/4)
Tail somite 3 (1/485) (2/4)
Trachea 2 (1/50) (2/2)
Urinary system 2 (1/50) (2/2)


Associated Images

Associated Images
  • Gross Morphology Embryo E14.5-E15.5
    6 Images
  • Histopathology
    8 Images
  • X-ray: XRay Images Skull Lateral Orientation
    12 Images
  • Eye Morphology: Images Ophthalmoscopy
    9 Images
  • X-ray: XRay Images Lateral Orientation
    12 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    12 Images
  • X-ray: XRay Images Dorso Ventral
    12 Images
  • Gross Pathology and Tissue Collection
    12 Images
  • Combined SHIRPA and Dysmorphology
    1 Images
  • Eye Morphology: Images Slit Lamp
    2 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ggnbp2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Ggnbp2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene