Gene: Clcc1

Order

Name chloride channel CLIC-like 1

Synonyms Mclc

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:2385186    Ensembl Gene    Ensembl Orthologs    My Genes    IDG   

Viability Homozygous - Lethal

Phenotype associations for Clcc1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Clcc1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Clcc1tm1b(KOMP)Mbp HOM Female Male embryonic day 9.5 0.0
abnormal embryo size Clcc1tm1b(KOMP)Mbp HET Male embryonic day 9.5 0.0
abnormal embryo turning Clcc1tm1b(KOMP)Mbp HOM Female Male embryonic day 9.5 0.0
embryonic growth retardation Clcc1tm1b(KOMP)Mbp HET Male embryonic day 9.5 0.0
embryonic growth retardation Clcc1tm1b(KOMP)Mbp HOM Female Male embryonic day 9.5 0.0
preweaning lethality, complete penetrance Clcc1tm1b(KOMP)Mbp HOM Female Male n/a 0.0
increased fasted circulating glucose level Clcc1tm1b(KOMP)Mbp HET Female Male postnatal 1.98E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Brain 2 No
Brainstem 2 No (2/2)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No (1/2)
Midbrain 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Submandibular gland 2 No (2/132) (2/2)
Testis 2 No (2/584) (1/2)
Thalamus 2 No
Thymus 2 No
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vascular system 2 No (2/2)
Vesicular gland 2 No
White adipose tissue 2 No (2/2)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    adipose tissue
    trunk
    postnatal mouse
    nervous system
    sensory organ
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (2/2)
Dorsal root ganglion 2 (1/47)
Ear 2 (1/485)
Embryo 2 (1/485) (2/2)
Eye 2 (1/485) (2/2)
Foot 2 (1/485) (2/2)
Forebrain 2 (1/485) (2/2)
Forelimb 2 (1/485) (2/2)
Fronto-nasal process 2 (1/48) Image Only
Hand 2 (1/485) (2/2)
Head 2 (5/485) (2/2)
Heart 2 (1/485) (2/2)
Hindbrain 2 (6/485) (2/2)
Hindlimb 2 (1/485) (2/2)
Liver 2 (1/485)
Lung 2 (1/485) Image Only
Mandibular process 2 (1/485) (2/2)
Maxillary process 2 (1/485) (2/2)
Midbrain 2 (1/485) (2/2)
Nose 2 (1/51) (2/2)
Oral cavity 2 (1/485) Image Only
Skin 2 (1/485) Image Only
Spinal cord 2 (1/50) (2/2)
Tail 2 (1/485) (2/2)
Tail somite 2 (1/485) (2/2)


Associated Images

Associated Images
  • Sleep Wake: Wake state (bmp file)
    8 Images
  • Gross Morphology Embryo E9.5
    6 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Clcc1tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Clcc1tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre)
Vector
Gene