Gene: Rab40c

Order

Name Rab40C, member RAS oncogene family

Synonyms RAR3

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:2183454    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Rab40c

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Rab40c data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
prenatal lethality Rab40ctm1b(KOMP)Wtsi HOM Female Male embryonic day 18.5 0.0
preweaning lethality, incomplete penetrance Rab40ctm1b(KOMP)Wtsi HOM Female Male n/a 0.0
increased circulating sodium level Rab40ctm1b(KOMP)Wtsi HET Female Male postnatal 5.89E-8
decreased mean corpuscular hemoglobin Rab40ctm1b(KOMP)Wtsi HET Female postnatal 1.45E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584) (2/2)
Stomach 2 No (12/584) (2/2)
Striatum 2 No (2/2)
Submandibular gland 2 No (2/132) (2/2)
Testis 2 No (2/584) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584)
Trachea 2 No (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vascular system 2 No (2/2)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485)
Dorsal root ganglion 2 (1/47)
Ear 2 (1/485)
Embryo 2 (1/485)
Eye 2 (1/485)
Foot 2 (1/485)
Forebrain 2 (1/485)
Forelimb 2 (1/485)
Fronto-nasal process 2 (1/48)
Hand 2 (1/485)
Head 2 (5/485)
Heart 2 (1/485)
Hindbrain 2 (6/485)
Hindlimb 2 (1/485)
Liver 2 (1/485)
Lung 2 (1/485)
Mandibular process 2 (1/485)
Maxillary process 2 (1/485)
Midbrain 2 (1/485)
Nose 2 (1/51)
Oral cavity 2 (1/485)
Skin 2 (1/485)
Spinal cord 2 (1/50)
Tail 2 (1/485)
Tail somite 2 (1/485)


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    11 Images
  • X-ray: XRay Images Skull Lateral Orientation
    11 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    11 Images
  • X-ray: XRay Images Forepaw
    11 Images
  • X-ray: XRay Images Lateral Orientation
    11 Images
  • Electroretinography 2: Rod and cone PDF
    4 Images
  • Combined SHIRPA and Dysmorphology
    4 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Rab40ctm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Rab40ctm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Rab40ctm119149(L1L2_Bact_P)
Vector
Gene