Gene: Rundc1

Order

Name RUN domain containing 1

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:2144506    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal     Homozygous - Subviable

Phenotype associations for Rundc1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Rundc1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Rundc1tm1a(EUCOMM)Wtsi HOM Female Male n/a 0.0
preweaning lethality, incomplete penetrance Rundc1tm1b(EUCOMM)Wtsi HOM Female Male n/a 0.0
decreased circulating HDL cholesterol level Rundc1tm1a(EUCOMM)Wtsi HET Female postnatal 3.04E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No (4/4)
Aorta 4 No (1/562) (3/4)
Blood vessel 4 No
Bone 4 No (1/539)
Brain 4 No (6/562) (4/4)
Brainstem 4 No (4/562) (4/4)
Brown adipose tissue 4 No
Cartilage tissue 4 No (1/562) (4/4)
Cerebellum 4 No (4/562) (4/4)
Cerebral cortex 4 No (5/562) (4/4)
Eye 4 No (1/562)
Gall bladder 4 No (4/4)
Heart 4 No (3/562) (4/4)
Hippocampus 4 No (5/562) (4/4)
Hypothalamus 4 No (4/562) (4/4)
Kidney 4 No (20/562) (4/4)
Large intestine 4 No (12/562) (4/4)
Liver 4 No
Lower urinary tract 4 No (3/562) (4/4)
Lung 4 No (3/562) (4/4)
Lymph node 4 No (1/562)
Mammary gland 4 No
Esophagus 4 No (4/4)
Olfactory lobe 4 No (4/4)
Ovary 4 No (1/562) (2/4)
Oviduct 4 No (2/562) (2/4)
Pancreas 4 No (6/562) (4/4)
Parathyroid gland 4 No (2/540) (4/4)
Peripheral nervous system 4 No (3/562) (4/4)
Peyer's patch 4 No
Pituitary gland 4 No (1/562) (4/4)
Prostate gland 4 No (5/562) (1/4)
Skeletal muscle tissue 4 No (2/4)
Skin 4 No (1/562)
Small intestine 4 No (11/562) (4/4)
Spinal cord 4 No (3/562) (4/4)
Spleen 4 No (4/562)
Stomach 4 No (9/562) (4/4)
Striatum 4 No (4/562) (4/4)
Testis 4 No (4/562) (2/4)
Thymus 4 No
Thyroid gland 4 No (16/562) (4/4)
Trachea 4 No (3/562) (4/4)
Uterus 4 No (2/562) (1/4)
White adipose tissue 4 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system postnatal mouse respiratory system digestive system cardiovascular system nervous system set of connective tissues reproductive system musculoskeletal system exocrine system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (35)
  • Rundc1tm1a(EUCOMM)Wtsi
    skeletal muscle tissue, HET, Female, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    pancreas, HET, Female, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    oesophagus, HET, Female, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    small intestine, HET, Female, WTSI

show all 35 images

trunk (28)
  • Rundc1tm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    pancreas, HET, Female, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    oesophagus, HET, Female, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    small intestine, HET, Female, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    large intestine, HET, Female, WTSI

show all 28 images

digestive system (8)
  • Rundc1tm1b(EUCOMM)Wtsi
    oesophagus, HET, Female, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    small intestine, HET, Female, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    large intestine, HET, Female, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    gall bladder, HET, Female, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    large intestine, HET, Female, WTSI

show all 8 images

nervous system (6)
  • Rundc1tm1b(EUCOMM)Wtsi
    trigeminal V nerve, peripheral nervous system, HET, Female, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    hippocampus, HET, Female, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    olfactory lobe, HET, Male, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    spinal cord, HET, Female, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    spinal cord, HET, Female, WTSI

show all 6 images

urinary system (5)
  • Rundc1tm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    kidney, HET, Female, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    kidney, HET, Female, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Male, WTSI
endocrine system (4)
  • Rundc1tm1a(EUCOMM)Wtsi
    thyroid gland, HET, Female, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    parathyroid gland, HET, Female, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    adrenal gland, HET, Female, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    adrenal gland, HET, Female, WTSI
reproductive system (4)
  • Rundc1tm1b(EUCOMM)Wtsi
    testis, HET, Male, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    ovary, HET, Female, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    uterus, HET, Female, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
cardiovascular system (2)
  • Rundc1tm1b(EUCOMM)Wtsi
    aorta, HET, Male, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    aorta, HET, Male, WTSI
musculoskeletal system (2)
  • Rundc1tm1a(EUCOMM)Wtsi
    skeletal muscle tissue, HET, Female, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    rib, cartilage tissue, HET, Female, WTSI
respiratory system (2)
  • Rundc1tm1b(EUCOMM)Wtsi
    lung, HET, Female, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    lung, HET, Female, WTSI
set of connective tissues (1)
  • Rundc1tm1b(EUCOMM)Wtsi
    rib, cartilage tissue, HET, Female, WTSI

Associated Images

Associated Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    29 Images
  • X-ray: XRay Images Dorso Ventral
    85 Images
  • X-ray: XRay Images Forepaw
    28 Images
  • X-ray: XRay Images Lateral Orientation
    54 Images
  • X-ray: XRay Images Skull Lateral Orientation
    27 Images
  • Anti-nuclear antibody assay
    6 Images
  • DSS Histology
    8 Images
  • Eye Morphology: Images Ophthalmoscopy
    5 Images
  • Eye Morphology: Images Slit Lamp
    2 Images
Legacy Phenotype Associated Images
Xray (239)
  • Rundc1tm1a(EUCOMM)Wtsi
    WT, Male, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    WT, Male, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    WT, Male, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    HET, Male, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    HET, Male, WTSI

show all 239 images

Eye Morphology (8)
  • Rundc1tm1a(EUCOMM)Wtsi
    corneal opacity, HET, Female, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    right eye, HET, Female, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    abnormal retinal pigmentation, HET, Male, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    abnormal retinal pigmentation, HET, Male, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    abnormal retinal pigmentation, right eye, HET, Female, WTSI

show all 8 images

Histology Slide (7)
  • Rundc1tm1b(EUCOMM)Wtsi
    TS20 eye, HET, Male, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    TS20 chorioallantoic placenta, HET, Male, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    TS20 forebrain, HET, Male, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    TS20 forebrain, HET, Male, WTSI
  • Rundc1tm1a(EUCOMM)Wtsi
    TS20 liver, HET, Unsexed, WTSI

show all 7 images

Embryo Dysmorphology (2)
  • Rundc1tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Rundc1tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Rundc1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Rundc1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Rundc1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Rundc1tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene