Gene: Fastkd5

Order

Name FAST kinase domains 5

Status ES CellsMice
em1
Mice
tm1
Mice
tm1.1
phenotype data available

Links MGI:2139469    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable     Homozygous - Lethal

Phenotype associations for Fastkd5

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Fastkd5 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Fastkd5tm1.1(KOMP)Vlcg HET Female Male embryonic day 12.5 0.0
embryonic growth retardation Fastkd5tm1.1(KOMP)Vlcg HET Female Male embryonic day 12.5 0.0
embryonic lethality prior to tooth bud stage Fastkd5tm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Fastkd5tm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
increased total body fat amount Fastkd5tm1.1(KOMP)Vlcg HET Male postnatal 4.21E-6
abnormal sleep behavior Fastkd5em1(IMPC)J HOM Female postnatal 1.25E-5
impaired righting response Fastkd5em1(IMPC)J HOM Male postnatal 5.29E-5
decreased circulating glucose level Fastkd5em1(IMPC)J HOM Female Male postnatal 6.89E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No (2/2)
Mammary gland 2 No (1/2)
Midbrain 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No (2/2)
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle 2 No (2/2)
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584) (2/2)
Stomach 2 No (12/584) (2/2)
Striatum 2 No (2/2)
Submandibular gland 2 No (2/132)
Testis 2 No (2/584) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584)
Trachea 2 No (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vascular system 2 No (2/2)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (2/2)
Dorsal root ganglion 2 (1/47) (2/2)
Ear 2 (1/485) (2/2)
Embryo 2 (1/485) (2/2)
Eye 2 (1/485) (2/2)
Foot 2 (1/485) (2/2)
Forebrain 2 (1/485) (2/2)
Forelimb 2 (1/485) (2/2)
Fronto-nasal process 2 (1/48) Image Only
Hand 2 (1/485) (2/2)
Head 2 (5/485) (2/2)
Heart 2 (1/485) (2/2)
Hindbrain 2 (6/485) (2/2)
Hindlimb 2 (1/485) (2/2)
Liver 2 (1/485) (2/2)
Lung 2 (1/485) Image Only
Mandibular process 2 (1/485) (2/2)
Maxillary process 2 (1/485) (2/2)
Midbrain 2 (1/485) (2/2)
Nose 2 (1/51) (2/2)
Oral cavity 2 (1/485) Image Only
Skin 2 (1/485) (2/2)
Spinal cord 2 (1/50) (2/2)
Tail 2 (1/485) (2/2)
Tail somite 2 (1/485)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • Sleep Wake: Wake state (bmp file)
    22 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Forepaw
    10 Images
  • Electroretinography 2: Rod and cone PDF
    3 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Fastkd5em1(IMPC)J Indel causing a Frameshift Mutation
Vector
Gene
Fastkd5tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Fastkd5tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene