Gene: Dbr1

Order

Name debranching RNA lariats 1

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:1931520    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Dbr1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Dbr1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
embryonic lethality prior to organogenesis Dbr1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
preweaning lethality, complete penetrance Dbr1tm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
decreased urine magnesium level Dbr1tm1.1(KOMP)Vlcg HET Female Male postnatal 1.54E-19
abnormal lens morphology Dbr1tm1.1(KOMP)Vlcg HET Female postnatal 4.29E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (2/2)
Aorta 2 No (1/562) (2/2)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (1/562) (2/2)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Epididymis 2 No (4/106) (1/2)
Esophagus 2 No (2/393) (2/2)
Eye 2 No (1/562) (2/2)
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562) (2/2)
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No (4/393) (2/2)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (2/2)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (1/393) (2/2)
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No (2/2)
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562) (2/2)
Stomach 2 No (9/562) (1/2)
Striatum 2 No (4/562) (2/2)
Submandibular gland 2 No (1/104) (1/2)
Testis 2 No (4/562) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (1/2)
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562) (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (2/562) (1/2)
Vascular system 2 No (1/393) (2/2)
Vesicular gland 2 No
White adipose tissue 2 No (2/2)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    musculoskeletal system
    adipose tissue
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/482) (2/2)
Dorsal root ganglion 2 (1/45) Image Only
Ear 2 (1/482) (2/2)
Embryo 2 (1/482) (2/2)
Eye 2 (1/482) (1/2)
Foot 2 (1/482) (2/2)
Forebrain 2 (1/482) (2/2)
Forelimb 2 (1/482) (2/2)
Fronto-nasal process 2 (1/46) Image Only
Hand 2 (1/482) (2/2)
Head 2 (5/482) (2/2)
Heart 2 (1/482) (2/2)
Hindbrain 2 (6/482) (2/2)
Hindlimb 2 (1/482) (2/2)
Liver 2 (1/482)
Lung 2 (1/482) Image Only
Mandibular process 2 (1/482) (2/2)
Maxillary process 2 (1/482) (2/2)
Midbrain 2 (1/482) (2/2)
Nose 2 (1/47) (2/2)
Oral cavity 2 (1/482) (1/2)
Skin 2 (1/482) (2/2)
Spinal cord 2 (1/46) (2/2)
Tail 2 (1/482) (2/2)
Tail somite 2 (1/482) (2/2)


Associated Images

Associated Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • Eye Morphology: Images Slit Lamp
    1 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Dbr1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Dbr1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Dbr1tm78661(L1L2_Bact_P)
Vector
Gene