Gene: Krit1

Order

Name KRIT1, ankyrin repeat containing

Synonyms
  • 2010007K12Rik
  • Krit1B
  • A630036P20Rik
  • Krit1
  • Krit1A
  • Ccm1

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:1930618    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Krit1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Krit1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal allantois morphology Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal blood vessel morphology Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal chorioallantoic fusion Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal embryo size Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal embryo size Krit1tm1.1(KOMP)Vlcg HET Female Male embryonic day 9.5 0.0
abnormal embryo turning Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal embryo turning Krit1tm1.1(KOMP)Vlcg HET Female embryonic day 9.5 0.0
abnormal forebrain development Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal heart looping Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal heart morphology Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal hindbrain development Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal left-right axis patterning Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal limb bud morphology Krit1tm1.1(KOMP)Vlcg HOM Male embryonic day 9.5 0.0
abnormal limb bud morphology Krit1tm1.1(KOMP)Vlcg HET Female embryonic day 9.5 0.0
abnormal midbrain development Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal neural tube closure Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal neural tube closure Krit1tm1.1(KOMP)Vlcg HET Female embryonic day 9.5 0.0
abnormal neural tube morphology Krit1tm1.1(KOMP)Vlcg HET Female embryonic day 9.5 0.0
abnormal neural tube morphology Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal optic vesicle formation Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal otic vesicle morphology Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal pericardium morphology Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal pharyngeal arch morphology Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal somite shape Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal tail bud morphology Krit1tm1.1(KOMP)Vlcg HET Female embryonic day 9.5 0.0
abnormal tail bud morphology Krit1tm1.1(KOMP)Vlcg HOM Male embryonic day 9.5 0.0
abnormal visceral yolk sac morphology Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
abnormal vitelline vasculature morphology Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
embryonic growth retardation Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
embryonic lethality prior to organogenesis Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
pale yolk sac Krit1tm1.1(KOMP)Vlcg HET Female embryonic day 9.5 0.0
pale yolk sac Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
pallor Krit1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
pallor Krit1tm1.1(KOMP)Vlcg HET Female Male embryonic day 9.5 0.0
preweaning lethality, complete penetrance Krit1tm1.1(KOMP)Vlcg HOM Female Male n/a 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Blood 2 No (1/2)
Bone marrow 2 No (1/2)
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cecum 2 No (12/383) (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No
Chest bone 2 No
Colon 2 No (12/127) (2/2)
Diaphragm 2 No (1/2)
Duodenum 2 No (2/127) (2/2)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No (2/2)
Gall bladder 2 No
Gonadal fat pad 2 No (1/2)
Harderian gland 2 No (1/2)
Heart 2 No
Hindlimb 2 No
Hippocampus 2 No
Hypothalamus 2 No
Ileum 2 No (14/127) (2/2)
Jejunum 2 No (6/127)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No (1/2)
Mesenteric lymph node 2 No
Mesenteric adipose tissue 2 No (1/2)
Midbrain 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Parotid gland 2 No
Penis 2 No (1/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584) (1/2)
Quadriceps 2 No (1/2)
Sciatic nerve 2 No
Skeletal muscle 2 No
Skin 2 No (1/2)
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584) (2/2)
Stomach 2 No (12/584) (2/2)
Stomach pyloric region 2 No
Striatum 2 No
Sublingual gland 2 No (2/2)
Submandibular gland 2 No (2/132) (1/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584) (1/2)
Tongue 2 No (5/127) (2/2)
Trachea 2 No (2/2)
Trigeminal V nerve 2 No (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vagina 2 No
Vas deferens 2 No (15/388) (1/2)
Vascular system 2 No
Vesicular gland 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system adipose tissue musculoskeletal system trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 5 (1/47) (5/5)
Axial skeleton 5 (1/51) (5/5)
Brain 5 (6/485) (5/5)
Central nervous system ganglion 5 (1/51)
Cranium 1 (1/46)
Dorsal root ganglion 5 (1/47)
Ear 5 (1/485) (5/5)
Embryo 5 (1/485) (5/5)
Outer ear 5 (1/47) (5/5)
Eye 5 (1/485) (5/5)
Foot 5 (1/485)
Forearm 5 (1/282) (5/5)
Forebrain 5 (1/485) (5/5)
Forelimb 5 (1/485) (5/5)
Fronto-nasal process 5 (1/48) (5/5)
Gut 5 (1/50) (5/5)
Hand 5 (1/485)
Head 5 (5/485) (5/5)
Head mesenchyme 5 (1/47) (5/5)
Heart 5 (1/485) (5/5)
Heart ventricle 5 (1/47) (1/5)
Hindbrain 5 (6/485) (4/5)
Hindlimb 5 (1/485) (5/5)
Intestine 5 (1/47) (5/5)
Liver 5 (1/485)
Lower leg 5 (1/282) (5/5)
Lung 5 (1/485)
Mandibular process 5 (1/485) (5/5)
Maxillary process 5 (1/485) (5/5)
Midbrain 5 (1/485) (5/5)
Nasal septum 5 (1/47) (5/5)
Nose 5 (1/51) (5/5)
Notochord 5 (1/47)
Oral cavity 5 (1/485) (5/5)
Outflow tract 5 (1/47) (5/5)
Pericardium 1 (1/46)
5 (7/25)
Skeleton 5 (1/51) (5/5)
Skin 5 (1/485) (5/5)
Spinal cord 5 (1/50) (5/5)
Tail 5 (1/485)
Tail somite 5 (1/485)
Thoracic vertebral cartilage condensation 5 (1/46) (5/5)
Trunk mesenchyme 5 (1/47) (5/5)
Umbilical artery embryonic part 5 (1/47) (5/5)
Umbilical vein embryonic part 5 (1/47) (5/5)
Upper arm 5 (1/282) (5/5)
Upper leg 5 (1/282) (5/5)
Vibrissa 5 (1/47)


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    40 Images
  • X-ray: XRay Images Lateral Orientation
    20 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Krit1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Krit1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Fixed Tissue
Krit1tm94595(L1L2_Bact_P)
Vector
Gene