Gene: Smoc1

Order

Name SPARC related modular calcium binding 1

Synonyms
  • SPARC-related protein
  • SRG
  • 2600002F22Rik

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:1929878    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Smoc1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Smoc1 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Smoc1tm1b(EUCOMM)Wtsi HOM Female Male n/a 0.0
abnormal digit morphology Smoc1tm1b(EUCOMM)Wtsi HOM Female Male postnatal 5.0E-10
abnormal snout morphology Smoc1tm1b(EUCOMM)Wtsi HOM Female Male postnatal 1.28E-9
syndactyly Smoc1tm1b(EUCOMM)Wtsi HOM Female Male postnatal 5.93E-9
abnormal maxilla morphology Smoc1tm1b(EUCOMM)Wtsi HOM Female Male postnatal 2.25E-8
abnormal cranium morphology Smoc1tm1b(EUCOMM)Wtsi HOM Female Male postnatal 2.89E-8
abnormal head size Smoc1tm1b(EUCOMM)Wtsi HOM Female postnatal 7.28E-8
abnormal gait Smoc1tm1b(EUCOMM)Wtsi HOM Female Male postnatal 9.55E-7
abnormal pelvic girdle bone morphology Smoc1tm1b(EUCOMM)Wtsi HOM Female postnatal 9.96E-7
decreased body weight Smoc1tm1a(EUCOMM)Wtsi HET Female Male postnatal 1.06E-6
abnormal coat/hair pigmentation Smoc1tm1a(EUCOMM)Wtsi HET Male postnatal 2.22E-6
abnormal behavior Smoc1tm1b(EUCOMM)Wtsi HET Female Male postnatal 2.61E-6
increased large unstained cell number Smoc1tm1b(EUCOMM)Wtsi HET Female postnatal 6.33E-6
mammalian phenotype Smoc1tm1a(EUCOMM)Wtsi HET Male postnatal 3.17E-5
increased mean platelet volume Smoc1tm1b(EUCOMM)Wtsi HET Female Male postnatal 7.01E-5
decreased erythrocyte cell number Smoc1tm1b(EUCOMM)Wtsi HET Female Male postnatal 7.75E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 Yes (2/415) (2/2)
Aorta 1 Yes (2/2)
Bone 1 No
Brain 1 Yes (2/2)
Brainstem 1 No
Brown adipose tissue 1 Yes (2/2)
Cartilage tissue 1 Yes (2/2)
Cerebellum 1 No
Cerebral cortex 1 No
Esophagus 1 No (7/415)
Eye 1 No
Gall bladder 1 No (2/2)
Heart 1 No
Hippocampus 1 No
Hypothalamus 1 No
Kidney 1 No (18/584)
Large intestine 1 No (10/584) (1/2)
Liver 1 No
Lower urinary tract 1 No (2/2)
Lung 1 No
Lymph node 1 No
Mammary gland 1 Yes (1/2)
Olfactory lobe 1 Yes (2/2)
Oral epithelium 1 No
Ovary 1 No (1/584)
Oviduct 1 No
Pancreas 1 No (5/584) (1/2)
Parathyroid gland 1 No
Peripheral nervous system 1 No
Peyer's patch 1 No
Pituitary gland 1 No
Prostate gland 1 No (12/584)
Skeletal muscle 1 No
Skin 1 No
Small intestine 1 No (9/584) (2/2)
Spinal cord 1 No
Spleen 1 No (2/584)
Stomach 1 No (12/584)
Striatum 1 No
Testis 1 No (2/584) (1/2)
Thymus 1 No
Thyroid gland 1 No (15/584) (1/2)
Trachea 1 No
Uterus 1 Yes (1/2)
Vascular system 1 Yes (1/2)
White adipose tissue 1 Yes (2/2)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    postnatal mouse
    digestive system
    cardiovascular system
    nervous system
    set of connective tissues
    reproductive system
    adipose tissue
    exocrine system
    integumental system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (4/4)
Ear 2 (1/485) (1/4)
Embryo 2 (1/485) (4/4)
Eye 2 (1/485) (4/4)
Foot 2 (1/485) (3/4)
Forebrain 2 (1/485) (4/4)
Forelimb 2 (1/485) (3/4)
Hand 2 (1/485) (2/4)
Head 2 (5/485) (4/4)
Heart 2 (1/485)
Hindbrain 2 (6/485) (4/4)
Hindlimb 2 (1/485) (3/4)
Liver 2 (1/485)
Lung 2 (1/485)
Mandibular process 2 (1/485)
Maxillary process 2 (1/485) (2/4)
Midbrain 2 (1/485) (3/4)
Oral cavity 2 (1/485) (1/4)
Skin 2 (1/485)
Tail 2 (1/485) (4/4)
Tail somite 2 (1/485) (4/4)


Associated Images

Associated Images
  • Echo: M-Mode Images
    44 Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    7 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    16 Images
  • X-ray: XRay Images Hind Leg and Hip
    2 Images
  • Adult LacZ: LacZ Images Wholemount
    15 Images
  • X-ray: XRay Images Lateral Orientation
    15 Images
  • X-ray: XRay Images Dorso Ventral
    15 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Smoc1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Smoc1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene