Gene: Atg16l1

Order

Name autophagy related 16-like 1 (S. cerevisiae)

Synonyms
  • APG16L
  • 1500009K01Rik
  • WDR30

Status ES CellsMice
tm1a
phenotype data available

Links MGI:1924290    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Atg16l1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Atg16l1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Atg16l1tm1a(EUCOMM)Wtsi HOM Female Male n/a 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/2)
Aorta 2 No
Blood vessel 2 No (2/2)
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (2/2)
Cerebellum 2 No
Cerebral cortex 2 No
Eye 2 No (2/2)
Gall bladder 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (2/2)
Lung 2 No (2/2)
Lymph node 2 No (2/2)
Mammary gland 2 No (1/2)
Esophagus 2 No (2/2)
Olfactory lobe 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Parathyroid gland 2 No (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No (2/2)
Pituitary gland 2 No
Prostate gland 2 No (12/584) (1/2)
Skeletal muscle tissue 2 No (2/2)
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584) (2/2)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584)
Trachea 2 No (2/2)
Uterus 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system adipose tissue trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (28)
  • Atg16l1tm1a(EUCOMM)Wtsi
    brown adipose tissue, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    white adipose tissue, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    skeletal muscle tissue, bone, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    eye, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI

show all 28 images

trunk (17)
  • Atg16l1tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    spleen, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    small intestine, peyer's patch, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    adrenal gland, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    liver, gall bladder, HET, Male, WTSI

show all 17 images

adipose tissue (4)
  • Atg16l1tm1a(EUCOMM)Wtsi
    brown adipose tissue, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    white adipose tissue, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    blood vessel, white adipose tissue, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    mammary gland, inguinal fat pad, HET, Female, WTSI
digestive system (4)
  • Atg16l1tm1a(EUCOMM)Wtsi
    small intestine, peyer's patch, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    liver, gall bladder, HET, Male, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    oesophagus, stomach, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    large intestine, HET, Female, WTSI
immune system (4)
  • Atg16l1tm1a(EUCOMM)Wtsi
    spleen, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    small intestine, peyer's patch, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    thymus, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    mesenteric lymph node, lymph node, HET, Female, WTSI
set of connective tissues (4)
  • Atg16l1tm1a(EUCOMM)Wtsi
    brown adipose tissue, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    white adipose tissue, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    blood vessel, white adipose tissue, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    mammary gland, inguinal fat pad, HET, Female, WTSI
cardiovascular system (3)
  • Atg16l1tm1a(EUCOMM)Wtsi
    blood vessel, skin, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    heart, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    blood vessel, white adipose tissue, HET, Female, WTSI
integumental system (3)
  • Atg16l1tm1a(EUCOMM)Wtsi
    blood vessel, skin, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    skin muscle, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    mammary gland, inguinal fat pad, HET, Female, WTSI
nervous system (3)
  • Atg16l1tm1a(EUCOMM)Wtsi
    brain, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    peripheral nervous system, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    spinal cord, HET, Female, WTSI
reproductive system (3)
  • Atg16l1tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    prostate gland, urinary bladder, lower urinary tract, HET, Male, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    ovary, oviduct, uterus, HET, Female, WTSI
urinary system (3)
  • Atg16l1tm1a(EUCOMM)Wtsi
    kidney, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    prostate gland, urinary bladder, lower urinary tract, HET, Male, WTSI
endocrine system (2)
  • Atg16l1tm1a(EUCOMM)Wtsi
    adrenal gland, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    trachea, thyroid gland, parathyroid gland, HET, Female, WTSI
exocrine system (2)
  • Atg16l1tm1a(EUCOMM)Wtsi
    prostate gland, urinary bladder, lower urinary tract, HET, Male, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    mammary gland, inguinal fat pad, HET, Female, WTSI
respiratory system (2)
  • Atg16l1tm1a(EUCOMM)Wtsi
    lung, HET, Female, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    trachea, thyroid gland, parathyroid gland, HET, Female, WTSI
musculoskeletal system (1)
  • Atg16l1tm1a(EUCOMM)Wtsi
    skeletal muscle tissue, bone, HET, Female, WTSI
sensory organ (1)
  • Atg16l1tm1a(EUCOMM)Wtsi
    eye, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (375)
  • Atg16l1tm1a(EUCOMM)Wtsi
    body, WT, Male, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    head, WT, Male, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    forearm, WT, Male, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    WT, Male, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    body, WT, Male, WTSI

show all 375 images

Dysmorphology (8)
  • Atg16l1tm1a(EUCOMM)Wtsi
    WT, Male, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    WT, Male, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    WT, Male, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    WT, Male, WTSI
  • Atg16l1tm1a(EUCOMM)Wtsi
    WT, Male, WTSI

show all 8 images

Skin Histopathology (1)
  • Atg16l1tm1a(EUCOMM)Wtsi
    back skin, HET, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Atg16l1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Atg16l1tm43715(pL1L2_GT2_DelLacZ_bsd)
Vector
Gene