Gene: Fam49b

Order

Name family with sequence similarity 49, member B

Synonyms 0910001A06Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1923520    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Fam49b

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Fam49b data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
Brain - process of degenerative change Fam49btm1b(KOMP)Wtsi HET Female Male postnatal 0.0
Brain - MPATH diagnostic term hydrocephalus Fam49btm1b(KOMP)Wtsi HET Female Male postnatal 0.0
Eye with optic nerve - developmental and structural abnormality Fam49btm1b(KOMP)Wtsi HOM Female postnatal 0.0
Eye with optic nerve - developmental and structural abnormality Fam49btm1b(KOMP)Wtsi HET Male postnatal 0.0
Spleen - hyperplasia Fam49btm1b(KOMP)Wtsi HET Male postnatal 0.0
Spleen - hyperplasia Fam49btm1b(KOMP)Wtsi HOM Female Male postnatal 0.0
edema Fam49btm1b(KOMP)Wtsi HOM Female Male embryonic day 15.5 0.0
male infertility Fam49btm1b(KOMP)Wtsi HOM Male postpartum stage 0.0
preweaning lethality, incomplete penetrance Fam49btm1b(KOMP)Wtsi HOM Female Male n/a 0.0
decreased circulating sodium level Fam49btm1b(KOMP)Wtsi HET Male postnatal 3.21E-5
decreased body length Fam49btm1b(KOMP)Wtsi HET Female Male postnatal 9.86E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
No expression data was found for this adult tab
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 1 (1/51)
Brain 2 (6/485)
Central nervous system ganglion 1 (1/51)
Ear 2 (1/485)
Embryo 2 (1/485)
Eye 2 (1/485)
Foot 2 (1/485)
Forebrain 2 (1/485)
Forelimb 2 (1/485)
Gut 1 (1/50) (1/2)
Hand 2 (1/485)
Head 2 (5/485)
Heart 2 (1/485) (1/3)
Hindbrain 2 (6/485)
Hindlimb 2 (1/485)
Liver 2 (1/485)
Lung 2 (1/485)
Mandibular process 2 (1/485)
Maxillary process 2 (1/485)
Midbrain 2 (1/485)
Nose 1 (1/51)
Oral cavity 2 (1/485)
1 (7/25) (1/2)
Skeleton 1 (1/51)
Skin 2 (1/485)
Spinal cord 1 (1/50)
Tail 2 (1/485)
Tail somite 2 (1/485)
Trachea 1 (1/50)
Urinary system 1 (1/50)


Associated Images

Associated Images
  • X-ray: XRay Images Skull Lateral Orientation
    13 Images
  • X-ray: XRay Images Lateral Orientation
    13 Images
  • X-ray: XRay Images Dorso Ventral
    13 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    13 Images
  • Eye Morphology: Images Ophthalmoscopy
    30 Images
  • Gross Pathology and Tissue Collection
    14 Images
  • Embryo LacZ: LacZ images wholemount
    4 Images
  • Histopathology
    5 Images
  • Combined SHIRPA and Dysmorphology
    1 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Fam49btm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Fam49btm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene