Gene: Dhcr24

Order

Name 24-dehydrocholesterol reductase

Synonyms
  • seladin-1
  • 5830417J06Rik
  • 3-beta-hydroxysterol delta-24 reductase
  • 2310076D10Rik

Status ES CellsMice
tm1a
phenotype data available

Links MGI:1922004    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Dhcr24

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Dhcr24 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Dhcr24tm1a(EUCOMM)Wtsi HOM Female Male n/a 0.0
decreased circulating triglyceride level Dhcr24tm1a(EUCOMM)Wtsi HET Female Male postnatal 1.49E-6
abnormal behavior Dhcr24tm1a(EUCOMM)Wtsi HET Female Male postnatal 7.11E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No (1/562)
Blood vessel 2 No
Bone 2 No (1/539)
Brain 2 No (6/562)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle tissue 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (4/562)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Uterus 2 No (2/562)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (3)
  • Dhcr24tm1a(EUCOMM)Wtsi
    ovary, HET, Female, WTSI
  • Dhcr24tm1a(EUCOMM)Wtsi
    thyroid gland, HET, Female, WTSI
  • Dhcr24tm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
trunk (2)
  • Dhcr24tm1a(EUCOMM)Wtsi
    ovary, HET, Female, WTSI
  • Dhcr24tm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
endocrine system (1)
  • Dhcr24tm1a(EUCOMM)Wtsi
    thyroid gland, HET, Female, WTSI
reproductive system (1)
  • Dhcr24tm1a(EUCOMM)Wtsi
    ovary, HET, Female, WTSI
urinary system (1)
  • Dhcr24tm1a(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (158)
  • Dhcr24tm1a(EUCOMM)Wtsi
    body, HET, Male, WTSI
  • Dhcr24tm1a(EUCOMM)Wtsi
    head, HET, Male, WTSI
  • Dhcr24tm1a(EUCOMM)Wtsi
    forearm, HET, Male, WTSI
  • Dhcr24tm1a(EUCOMM)Wtsi
    forearm, HET, Male, WTSI
  • Dhcr24tm1a(EUCOMM)Wtsi
    body, HET, Male, WTSI

show all 158 images

Skin Histopathology (3)
  • Dhcr24tm1a(EUCOMM)Wtsi
    back skin, HET, Female, WTSI
  • Dhcr24tm1a(EUCOMM)Wtsi
    back skin, HET, Female, WTSI
  • Dhcr24tm1a(EUCOMM)Wtsi
    back skin, HET, Female, WTSI

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Dhcr24tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene