Gene: Klhl21

Order

Name kelch-like 21

Synonyms 1810045K06Rik

Status ES CellsMice
tm1a
phenotype data available

Links MGI:1919288    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Klhl21

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Klhl21 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Klhl21tm1a(KOMP)Wtsi HOM Female Male n/a 0.0
decreased CD4-positive, alpha beta T cell number Klhl21tm1a(KOMP)Wtsi HET Male postnatal 3.22E-5
decreased T cell number Klhl21tm1a(KOMP)Wtsi HET Male postnatal 3.93E-5
decreased circulating creatinine level Klhl21tm1a(KOMP)Wtsi HET Female postnatal 4.45E-5
increased circulating creatinine level Klhl21tm1a(KOMP)Wtsi HET Male postnatal 4.45E-5

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Associated Images
  • DSS Histology
    8 Images
  • X-ray: XRay Images Dorso Ventral
    42 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    15 Images
  • X-ray: XRay Images Lateral Orientation
    28 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • X-ray: XRay Images Forepaw
    13 Images
Legacy Phenotype Associated Images
Xray (70)
  • Klhl21tm1a(KOMP)Wtsi
    HET, Female, WTSI
  • Klhl21tm1a(KOMP)Wtsi
    HET, Female, WTSI
  • Klhl21tm1a(KOMP)Wtsi
    HET, Female, WTSI
  • Klhl21tm1a(KOMP)Wtsi
    HET, Female, WTSI
  • Klhl21tm1a(KOMP)Wtsi
    HET, Female, WTSI

show all 70 images

Embryo Dysmorphology (3)
  • Klhl21tm1a(KOMP)Wtsi
    HOM, Male, WTSI
  • Klhl21tm1a(KOMP)Wtsi
    HOM, Male, WTSI
  • Klhl21tm1a(KOMP)Wtsi
    HOM, Male, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Klhl21tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene