Gene: Ddx54

Order

Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 54

Synonyms
  • DP97
  • APR-5
  • 2410015A15Rik

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:1919240    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Ddx54

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ddx54 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Ddx54tm1.1(KOMP)Vlcg HET Male embryonic day 9.5 0.0
embryonic lethality prior to organogenesis Ddx54tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Ddx54tm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
enlarged heart Ddx54tm1.1(KOMP)Vlcg HET Male postnatal 0.0
preweaning lethality, complete penetrance Ddx54tm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
decreased vertical activity Ddx54tm1.1(KOMP)Vlcg HET Female Male postnatal 2.97E-8
decreased eosinophil cell number Ddx54tm1.1(KOMP)Vlcg HET Female Male postnatal 4.14E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (2/2)
Aorta 2 No (1/562)
Bone 2 No (1/539) (2/2)
Brain 2 No (6/562)
Brainstem 2 No (4/562)
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Esophagus 2 No (2/393)
Eye 2 No (1/562)
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562)
Liver 2 No (2/2)
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562) (2/2)
Mammary gland 2 No
Olfactory lobe 2 No (4/393)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562) (1/2)
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562) (2/2)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562)
Urinary bladder 2 No (1/2)
Uterus 2 No (2/562)
Vascular system 2 No (1/393)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    postnatal mouse
    digestive system
    reproductive system
    immune system
    musculoskeletal system exocrine system
    trunk
    urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    11 Images
  • X-ray: XRay Images Dorso Ventral
    9 Images
  • Adult LacZ: LacZ Images Section
    6 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ddx54tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Fixed Tissue
Paraffin-embedded Sections
Ddx54tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Ddx54tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene