Gene: Dynll1

Order

Name dynein light chain LC8-type 1

Synonyms
  • DLC8
  • 8kDa LC
  • Pin
  • Dnclc1

Status ES CellsMice
tm1
phenotype data available

Links MGI:1861457    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Dynll1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Dynll1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Dynll1tm1(KOMP)Wtsi HOM Female Male n/a 0.0
increased circulating alkaline phosphatase level Dynll1tm1(KOMP)Wtsi HET Female postnatal 4.59E-5

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Associated Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • X-ray: XRay Images Lateral Orientation
    28 Images
  • X-ray: XRay Images Dorso Ventral
    41 Images
  • X-ray: XRay Images Forepaw
    13 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
Legacy Phenotype Associated Images
Xray (84)
  • Dynll1tm1(KOMP)Wtsi
    HET, Male, WTSI
  • Dynll1tm1(KOMP)Wtsi
    HET, Male, WTSI
  • Dynll1tm1(KOMP)Wtsi
    HET, Male, WTSI
  • Dynll1tm1(KOMP)Wtsi
    WT, Female, WTSI
  • Dynll1tm1(KOMP)Wtsi
    WT, Female, WTSI

show all 84 images

Eye Morphology (2)
  • Dynll1tm1(KOMP)Wtsi
    left eye, eyelids fail to open, HET, Female, WTSI
  • Dynll1tm1(KOMP)Wtsi
    abnormal placement of pupils, abnormal pupil morphology, HET, Female, WTSI
Skin Histopathology (1)
  • Dynll1tm1(KOMP)Wtsi
    back skin, HET, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Dynll1tm1(KOMP)Wtsi Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Dynll1tm1(KOMP)Mbp Reporter-tagged deletion allele (with selection cassette)
Vector
Gene