Gene: Map2k7

Order

Name mitogen-activated protein kinase kinase 7

Synonyms
  • Jnkk2
  • MAP kinase kinase 7
  • 5930412N11Rik
  • Prkmk7
  • MKK7
  • sek2

Status ES CellsMice
tm1a
phenotype data available

Links MGI:1346871    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Map2k7

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Map2k7 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Map2k7tm1a(EUCOMM)Wtsi HOM Female Male n/a 0.0
decreased circulating creatinine level Map2k7tm1a(EUCOMM)Wtsi HET Female postnatal 9.07E-5

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    43 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • X-ray: XRay Images Forepaw
    14 Images
  • X-ray: XRay Images Lateral Orientation
    27 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
Legacy Phenotype Associated Images
Xray (100)
  • Map2k7tm1a(EUCOMM)Wtsi
    HET, Male, WTSI
  • Map2k7tm1a(EUCOMM)Wtsi
    WT, Female, WTSI
  • Map2k7tm1a(EUCOMM)Wtsi
    WT, Female, WTSI
  • Map2k7tm1a(EUCOMM)Wtsi
    WT, Female, WTSI
  • Map2k7tm1a(EUCOMM)Wtsi
    WT, Female, WTSI

show all 100 images

Eye Morphology (2)
  • Map2k7tm1a(EUCOMM)Wtsi
    right eye, HET, Female, WTSI
  • Map2k7tm1a(EUCOMM)Wtsi
    persistence of hyaloid vascular system, HET, Female, WTSI
Skin Histopathology (1)
  • Map2k7tm1a(EUCOMM)Wtsi
    back skin, HET, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Map2k7tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Map2k7tm1(NCOM)Cmhd Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Map2k7tm42422(L1L2_gt0)
Vector
Gene