Gene: Adam23

Order

Name a disintegrin and metallopeptidase domain 23

Synonyms MDC3

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:1345162    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Adam23

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Adam23 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Adam23tm1b(EUCOMM)Hmgu HOM Female Male n/a 0.0
abnormal tooth morphology Adam23tm1b(EUCOMM)Hmgu HET Female postnatal 1.05E-9

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (2/2)
Aorta 2 No (1/562)
Bone 2 No (1/539)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Esophagus 2 No (2/393) (2/2)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (20/562)
Large intestine 2 No (12/562) (1/2)
Liver 2 No
Lower urinary tract 2 No (3/562) (2/2)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Olfactory lobe 2 No (4/393) (2/2)
Oral epithelium 2 No
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540) (2/2)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562) (2/2)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562) (1/2)
Trachea 2 No (3/562)
Uterus 2 No (2/562) (1/2)
Vascular system 2 No (1/393)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    postnatal mouse
    digestive system
    nervous system
    reproductive system
    trunk
    urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • Echo: M-Mode Images
    32 Images
  • Adult LacZ: LacZ Images Wholemount
    12 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    4 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Adam23tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Adam23tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene