Gene: S100a6

Order

Name S100 calcium binding protein A6 (calcyclin)

Synonyms
  • PRA
  • CALCYCLIN
  • Cacy
  • 2A9
  • 5B10

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1339467    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for S100a6

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all S100a6 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
enlarged seminal vesicle S100a6tm1b(KOMP)Wtsi HET Male postnatal 0.0
preweaning lethality, incomplete penetrance S100a6tm1b(KOMP)Wtsi HOM Female Male n/a 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No (2/415)
Aorta 4 No
Blood 4 No
Bone marrow 4 No
Brain 4 No (2/4)
Brainstem 4 No
Brown adipose tissue 4 No
Cartilage tissue 4 No
Cecum 4 No (12/383) (3/4)
Cerebellum 4 No
Cerebral cortex 4 No
Chest bone 4 No (2/4)
Colon 4 No (12/127) (4/4)
Diaphragm 4 No
Duodenum 4 No (2/127) (3/4)
Epididymis 4 No (18/134) (2/4)
Esophagus 4 No (7/415) (1/4)
Eye 4 No (3/4)
Gall bladder 4 No
Gonadal fat pad 4 No
Harderian gland 4 No
Heart 4 No
Hindlimb 4 No
Hippocampus 4 No
Hypothalamus 4 No
Ileum 4 No (14/127) (4/4)
Jejunum 4 No (6/127) (2/4)
Kidney 4 No (18/584) (4/4)
Large intestine 4 No (10/584)
Liver 4 No (1/4)
Lower urinary tract 4 No
Lung 4 No
Lymph node 4 No
Mammary gland 4 No
Mesenteric lymph node 4 No
Mesenteric adipose tissue 4 No
Midbrain 4 No (3/4)
Olfactory lobe 4 No (3/4)
Ovary 4 No (1/584) (2/4)
Oviduct 4 No (2/4)
Pancreas 4 No (5/584)
Parathyroid gland 4 No
Parotid gland 4 No
Penis 4 No (2/4)
Peripheral nervous system 4 No
Peyer's patch 4 No
Pituitary gland 4 No
Prostate gland 4 No (12/584) (1/4)
Quadriceps 4 No (1/4)
Sciatic nerve 4 No
Skeletal muscle 4 No
Skin 4 No (4/4)
Small intestine 4 No (9/584)
Spinal cord 4 No
Spleen 4 No (2/584) (1/4)
Stomach 4 No (12/584) (3/4)
Stomach pyloric region 4 No
Striatum 4 No
Sublingual gland 4 No
Submandibular gland 4 No (2/132)
Testis 4 No (2/584) (2/4)
Thymus 4 No (2/4)
Thyroid gland 4 No (15/584)
Tongue 4 No (5/127) (4/4)
Trachea 4 No (3/4)
Trigeminal V nerve 4 No
Urinary bladder 4 No (4/4)
Uterus 4 No
Vagina 4 No
Vas deferens 4 No (15/388) (2/4)
Vascular system 4 No
Vesicular gland 4 No (2/4)
White adipose tissue 4 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system digestive system nervous system sensory organ reproductive system immune system musculoskeletal system exocrine system integumental system trunk urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 1 (1/51)
Brain 6 (6/485) (2/9)
Central nervous system ganglion 1 (1/51)
Ear 6 (1/485)
Embryo 6 (1/485) (2/9)
Eye 6 (1/485)
Foot 6 (1/485)
Forebrain 6 (1/485) (1/9)
Forelimb 6 (1/485)
Gut 1 (1/50)
Hand 6 (1/485)
Head 6 (5/485)
Heart 6 (1/485)
Hindbrain 6 (6/485)
Hindlimb 6 (1/485)
Liver 6 (1/485)
Lung 6 (1/485)
Mandibular process 6 (1/485)
Maxillary process 6 (1/485)
Midbrain 6 (1/485)
Nose 1 (1/51) (2/2)
Oral cavity 6 (1/485)
Skeleton 1 (1/51)
Skin 6 (1/485) (2/9)
Spinal cord 1 (1/50)
Tail 6 (1/485)
Tail somite 6 (1/485)
Trachea 1 (1/50)
Urinary system 1 (1/50)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    19 Images
  • X-ray: XRay Images Dorso Ventral
    41 Images
  • Embryo LacZ: LacZ images wholemount
    29 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
S100a6tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
S100a6tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Fixed Tissue