Gene: Arid3a

Order

Name AT rich interactive domain 3A (BRIGHT-like)

Synonyms
  • Dri1
  • Bright

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:1328360    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Arid3a

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Arid3a data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Arid3atm1b(KOMP)Wtsi HOM embryonic day 12.5 0.0
abnormal limb bud morphology Arid3atm1b(KOMP)Wtsi HOM embryonic day 12.5 0.0
abnormal placenta morphology Arid3atm1b(KOMP)Wtsi HOM embryonic day 15.5 0.0
hemorrhage Arid3atm1b(KOMP)Wtsi HOM embryonic day 12.5 0.0
preweaning lethality, complete penetrance Arid3atm1b(KOMP)Wtsi HOM Female Male n/a 0.0
decreased body length Arid3atm1b(KOMP)Wtsi HET Female Male postnatal 5.95E-6
abnormal bone structure Arid3atm1b(KOMP)Wtsi HET Female Male postnatal 1.14E-5
decreased anxiety-related response Arid3atm1b(KOMP)Wtsi HET Male postnatal 3.37E-5
abnormal lens morphology Arid3atm1b(KOMP)Wtsi HET Female postnatal 5.45E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (2/2)
Aorta 2 No (1/562) (1/2)
Bone marrow 2 No (2/2)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (1/562) (2/2)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Epididymis 2 No (4/106) (1/2)
Esophagus 2 No (2/393)
Eye 2 No (1/562) (2/2)
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (1/2)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562) (2/2)
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No (4/393) (2/2)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (1/2)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No (1/2)
Skin 2 No (1/562) (1/2)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562) (2/2)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562) (2/2)
Submandibular gland 2 No (1/104) (2/2)
Testis 2 No (4/562) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (1/2)
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562) (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (2/562) (1/2)
Vascular system 2 No (1/393)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    musculoskeletal system
    adipose tissue
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/482) (1/3)
Dorsal root ganglion 1 (1/45) Image Only
Ear 2 (1/482) (1/3)
Embryo 2 (1/482) (2/3)
Eye 2 (1/482) (2/3)
Foot 2 (1/482) (2/3)
Forebrain 2 (1/482) (1/3)
Forelimb 2 (1/482) (2/3)
Fronto-nasal process 1 (1/46) Image Only
Hand 2 (1/482) (2/3)
Head 2 (5/482) (2/3)
Heart 2 (1/482) Image Only
Hindbrain 2 (6/482) (1/3)
Hindlimb 2 (1/482) (2/3)
Liver 2 (1/482) Image Only
Lung 2 (1/482) Image Only
Mandibular process 2 (1/482) (2/3)
Maxillary process 2 (1/482) (2/3)
Midbrain 2 (1/482) (1/3)
Nose 1 (1/47) (1/1)
Oral cavity 2 (1/482) Image Only
Skin 2 (1/482) (2/3)
Spinal cord 1 (1/46) (1/1)
Tail 2 (1/482) (2/3)
Tail somite 2 (1/482) (1/3)


Associated Images

Associated Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    13 Images
  • X-ray: XRay Images Skull Lateral Orientation
    13 Images
  • Electroretinography: Cone waveform (pdf format)
    4 Images
  • X-ray: XRay Images Lateral Orientation
    13 Images
  • X-ray: XRay Images Forepaw
    13 Images
  • Electroretinography: Rod waveform (pdf format)
    4 Images
  • X-ray: XRay Images Dorso Ventral
    13 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • Eye Morphology: Images Slit Lamp
    1 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Arid3atm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Arid3atm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene