Gene: Vamp3

Order

Name vesicle-associated membrane protein 3

Synonyms
  • ceb
  • cellubrevin
  • VAMP-3
  • D130027G05Rik

Status ES CellsMice
tm2a
Mice
tm2b
phenotype data available

Links MGI:1321389    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Vamp3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Vamp3 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Vamp3tm2b(EUCOMM)Wtsi HOM Female Male n/a 0.0
increased B cell number Vamp3tm2b(EUCOMM)Wtsi HOM Female Male postnatal 9.0E-7
increased mature B cell number Vamp3tm2b(EUCOMM)Wtsi HOM Female Male postnatal 9.0E-7
decreased total body fat amount Vamp3tm2b(EUCOMM)Wtsi HOM Female Male postnatal 3.27E-6
abnormal vibrissa morphology Vamp3tm2b(EUCOMM)Wtsi HOM Male postnatal 3.85E-6
decreased eosinophil cell number Vamp3tm2b(EUCOMM)Wtsi HOM Female Male postnatal 2.23E-5
increased circulating alkaline phosphatase level Vamp3tm2b(EUCOMM)Wtsi HOM Female postnatal 5.52E-5
abnormal bone structure Vamp3tm2b(EUCOMM)Wtsi HOM Female Male postnatal 9.78E-5

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    40 Images
  • X-ray: XRay Images Lateral Orientation
    28 Images
  • X-ray: XRay Images Forepaw
    12 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • Anti-nuclear antibody assay
    6 Images
  • DSS Histology
    4 Images
Legacy Phenotype Associated Images
Xray (68)
  • Vamp3tm2b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Vamp3tm2b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Vamp3tm2b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Vamp3tm2b(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Vamp3tm2b(EUCOMM)Wtsi
    HOM, Male, WTSI

show all 68 images

Brain Histopathology (6)
  • Vamp3tm2b(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Vamp3tm2b(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Vamp3tm2b(EUCOMM)Wtsi
    anterior commissure, decreased anterior commissure size, HOM, Male, WTSI
  • Vamp3tm2b(EUCOMM)Wtsi
    anterior commissure, decreased anterior commissure size, HOM, Male, WTSI
  • Vamp3tm2b(EUCOMM)Wtsi
    anterior commissure, decreased anterior commissure size, HOM, Male, WTSI

show all 6 images

Dysmorphology (4)
  • Vamp3tm2b(EUCOMM)Wtsi
    hindlimb, abnormal digit morphology, HOM, Male, WTSI
  • Vamp3tm2b(EUCOMM)Wtsi
    head, abnormal snout morphology, upturned snout, HOM, Male, WTSI
  • Vamp3tm2b(EUCOMM)Wtsi
    head, abnormal snout morphology, asymmetric snout, malocclusion, HOM, Male, WTSI
  • Vamp3tm2b(EUCOMM)Wtsi
    head, abnormal snout morphology, asymmetric snout, malocclusion, HOM, Male, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Vamp3tm2b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Vamp3tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Vamp3tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Vamp3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene