Gene: Cdk12


Name cyclin-dependent kinase 12

  • Crk7
  • D11Ertd752e
  • Crkrs
  • 1810022J16Rik

Status ES CellsMice
phenotype data available

Links MGI:1098802    Ensembl Gene    Ensembl Orthologs    My Genes    IDG   

Viability Homozygous - Lethal

Phenotype associations for Cdk12

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Cdk12 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Cdk12em1(IMPC)Tcp HET Female embryonic day 9.5 0.0
embryonic lethality prior to organogenesis Cdk12em1(IMPC)Tcp HOM Female Male embryonic day 9.5 0.0
preweaning lethality, complete penetrance Cdk12em1(IMPC)Tcp HOM Female Male n/a 0.0
decreased circulating HDL cholesterol level Cdk12em1(IMPC)Tcp HET Male postnatal 7.7E-6
decreased circulating serum albumin level Cdk12em1(IMPC)Tcp HET Male postnatal 2.25E-5

Download data as: TSV XLS


Expression data not available

Associated Images

Associated Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • Eye Morphology: Images Slit Lamp
    3 Images
  • Eye Morphology: Images Ophthalmoscopy
    27 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Cdk12em1(IMPC)Tcp Exon Deletion
Cdk12tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Cdk12tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)