Gene: Anapc4

Order

Name anaphase promoting complex subunit 4

Synonyms
  • D5Ertd249e
  • APC4
  • 2610306D21Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1098673    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Anapc4

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Anapc4 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Anapc4tm1b(EUCOMM)Wtsi HET Female Male embryonic day 9.5 0.0
embryonic growth retardation Anapc4tm1b(EUCOMM)Wtsi HET Female Male embryonic day 9.5 0.0
embryonic lethality prior to organogenesis Anapc4tm1b(EUCOMM)Wtsi HOM Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Anapc4tm1b(EUCOMM)Wtsi HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Anapc4tm1b(EUCOMM)Wtsi HOM Female Male n/a 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562)
Bone 2 No (1/539)
Brain 2 No (6/562)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cecum 2 No (1/355)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Esophagus 2 No (2/393)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Olfactory lobe 2 No (4/393)
Oral epithelium 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562) (1/2)
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562)
Trigeminal V nerve 2 No
Uterus 2 No (2/562)
Vas deferens 2 No (1/360)
Vascular system 2 No (1/393)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    postnatal mouse
    reproductive system
    exocrine system
    trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2 (1/45)
Axial skeleton 2 (1/47)
Brain 2 (6/482)
Central nervous system ganglion 2 (1/47)
Cranium 2 (1/44)
Dorsal root ganglion 2 (1/45)
Ear 2 (1/482)
Embryo 2 (1/482)
Outer ear 2 (1/45)
Eye 2 (1/482)
Femur pre-cartilage condensation 2 (1/44)
Foot 2 (1/482)
Forearm 2 (1/280)
Forebrain 2 (1/482)
Forelimb 2 (1/482)
Fronto-nasal process 2 (1/46)
Gut 2 (1/46)
Hand 2 (1/482)
Head 2 (5/482)
Head mesenchyme 2 (1/45)
Heart 2 (1/482)
Heart ventricle 2 (1/45)
Hindbrain 2 (6/482)
Hindlimb 2 (1/482)
Humerus pre-cartilage condensation 2 (1/44)
Inner ear 2 (1/44)
Intestine 2 (1/45)
Liver 2 (1/482)
Lower leg 2 (1/280)
Lung 2 (1/482)
Mandibular process 2 (1/482)
Maxillary process 2 (1/482)
Mesonephros of female 2 (1/44)
Mesonephros of male 2 (1/44)
Metanephros 2 (1/44)
Midbrain 2 (1/482)
Nasal septum 2 (1/45)
Nose 2 (1/47)
Notochord 2 (1/45)
Oral cavity 2 (1/482)
Outflow tract 2 (1/45)
Pancreas 2 (1/44)
Pericardium 2 (1/44)
Pharynx 2 (1/44)
Radius-ulna pre-cartilage condensation 2 (1/44)
Rib pre-cartilage condensation 2 (1/44)
Skeleton 2 (1/47)
Skin 2 (1/482)
Spinal cord 2 (1/46)
Stomach 2 (1/44)
Tail 2 (1/482)
Tail somite 2 (1/482)
Thoracic vertebral cartilage condensation 2 (1/44)
Tongue 2 (1/44)
Trachea 2 (1/46)
Trunk mesenchyme 2 (1/45)
Umbilical artery embryonic part 2 (1/45)
Umbilical vein embryonic part 2 (1/45)
Upper arm 2 (1/280)
Upper leg 2 (1/280)
Urinary system 2 (1/46)
Vibrissa 2 (1/45)


Associated Images

Associated Images
  • Adult LacZ: LacZ Images Wholemount
    3 Images
  • X-ray: XRay Images Dorso Ventral
    14 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • Embryo LacZ: LacZ images wholemount
    4 Images
  • X-ray: XRay Images Lateral Orientation
    14 Images
  • X-ray: XRay Images Forepaw
    14 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Anapc4tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Anapc4tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene