Gene: Atp5b

Order

Name ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:107801    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Atp5b

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Atp5b data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
Skin - hypoplasia Atp5btm1b(EUCOMM)Hmgu HET Female postnatal 0.0
embryonic lethality prior to organogenesis Atp5btm1b(EUCOMM)Hmgu HOM Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Atp5btm1b(EUCOMM)Hmgu HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Atp5btm1b(EUCOMM)Hmgu HOM Female Male n/a 0.0
abnormal sensory capabilities/reflexes/nociception Atp5btm1b(EUCOMM)Hmgu HET Female postnatal 6.93E-5
decreased prepulse inhibition Atp5btm1b(EUCOMM)Hmgu HET Male postnatal 6.93E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
No expression data was found for this adult tab
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2 (1/51) (2/2)
Brain 8 (6/485) (2/8)
Central nervous system ganglion 2 (1/51) (2/2)
Ear 8 (1/485) (2/8)
Embryo 8 (1/485) (2/8)
Eye 8 (1/485) (2/8)
Foot 8 (1/485) (2/8)
Forebrain 8 (1/485) (2/8)
Forelimb 8 (1/485) (2/8)
Gut 2 (1/50) (2/2)
Hand 8 (1/485) (2/8)
Head 8 (5/485) (2/8)
Heart 8 (1/485) (2/8)
Hindbrain 8 (6/485) (2/8)
Hindlimb 8 (1/485) (2/8)
Liver 8 (1/485) (2/8)
Lung 8 (1/485) (2/8)
Mandibular process 8 (1/485) (2/8)
Maxillary process 8 (1/485) (2/8)
Midbrain 8 (1/485) (2/8)
Nose 2 (1/51) (2/2)
Oral cavity 8 (1/485) (2/8)
2 (7/25) (2/2)
Skeleton 2 (1/51) (2/2)
Skin 8 (1/485) (2/8)
Spinal cord 2 (1/50) (2/2)
Tail 8 (1/485) (2/8)
Tail somite 8 (1/485) (2/8)
Trachea 2 (1/50) (2/2)
Urinary system 2 (1/50) (2/2)


Associated Images

Associated Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • Gross Pathology and Tissue Collection
    8 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • Combined SHIRPA and Dysmorphology
    1 Images
  • Histopathology
    2 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Atp5btm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Atp5btm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Atp5btm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene