Gene: Lyst

Order

Name lysosomal trafficking regulator

Synonyms D13Sfk13

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:107448    Ensembl Gene    Ensembl Orthologs    My Genes   

Phenotype associations for Lyst

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Lyst data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
Eye with optic nerve - developmental dysplasia Lysttm1b(EUCOMM)Wtsi HOM Female postnatal 0.0
abnormal coat/hair pigmentation Lysttm1b(EUCOMM)Wtsi HOM Female Male postnatal 2.38E-21
abnormal iris morphology Lysttm1b(EUCOMM)Wtsi HOM Female Male postnatal 3.62E-16
increased lymphocyte cell number Lysttm1b(EUCOMM)Wtsi HOM Female Male postnatal 1.4E-5
increased mean corpuscular volume Lysttm1b(EUCOMM)Wtsi HOM Female Male postnatal 2.17E-5
increased fasted circulating glucose level Lysttm1b(EUCOMM)Wtsi HOM Female Male postnatal 3.52E-5
decreased body length Lysttm1b(EUCOMM)Wtsi HOM Female Male postnatal 6.92E-5

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Associated Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Eye Morphology: Images Slit Lamp
    11 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • Eye Morphology: Images Ophthalmoscopy
    14 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • Gross Pathology and Tissue Collection
    8 Images
  • Combined SHIRPA and Dysmorphology
    15 Images
  • Histopathology
    2 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Lysttm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Lysttm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene