Gene: Cox7c

Order

Name cytochrome c oxidase subunit 7C

Synonyms
  • Cox7c1
  • COXVIIc

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:103226    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Cox7c

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Cox7c data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Cox7ctm1b(KOMP)Mbp HOM embryonic day 12.5 0.0
abnormal embryo size Cox7ctm1b(KOMP)Mbp HOM Female Male embryonic day 15.5 0.0
abnormal limb bud morphology Cox7ctm1b(KOMP)Mbp HOM embryonic day 12.5 0.0
abnormal placenta development Cox7ctm1b(KOMP)Mbp HOM embryonic day 12.5 0.0
abnormal placenta morphology Cox7ctm1b(KOMP)Mbp HOM embryonic day 12.5 0.0
abnormal placenta size Cox7ctm1b(KOMP)Mbp HOM embryonic day 12.5 0.0
abnormal placenta size Cox7ctm1b(KOMP)Mbp HOM Female Male embryonic day 15.5 0.0
abnormal skin coloration Cox7ctm1b(KOMP)Mbp HOM Female Male embryonic day 15.5 0.0
embryonic growth retardation Cox7ctm1b(KOMP)Mbp HOM embryonic day 12.5 0.0
pallor Cox7ctm1b(KOMP)Mbp HOM embryonic day 12.5 0.0
preweaning lethality, complete penetrance Cox7ctm1b(KOMP)Mbp HOM Female Male n/a 0.0
increased fasted circulating glucose level Cox7ctm1b(KOMP)Mbp HET Female Male postnatal 4.73E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (2/2)
Aorta 2 No (1/562) (2/2)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562) (2/2)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Epididymis 2 No (4/106) (1/2)
Esophagus 2 No (2/393) (2/2)
Eye 2 No (1/562) (2/2)
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562)
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No (4/393) (2/2)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (2/2)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562) (1/2)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562)
Submandibular gland 2 No (1/104) (2/2)
Testis 2 No (4/562) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (16/562) (1/2)
Trachea 2 No (3/562) (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (2/562) (1/2)
Vascular system 2 No (1/393) (2/2)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/482) (2/3)
Dorsal root ganglion 1 (1/45) Image Only
Ear 2 (1/482) Image Only
Embryo 2 (1/482) (2/3)
Eye 2 (1/482) (2/3)
Foot 2 (1/482) (1/3)
Forebrain 2 (1/482) (2/3)
Forelimb 2 (1/482) (2/3)
Fronto-nasal process 1 (1/46) Image Only
Hand 2 (1/482) (1/3)
Head 2 (5/482) (2/3)
Heart 2 (1/482) (2/3)
Hindbrain 2 (6/482) (2/3)
Hindlimb 2 (1/482) (2/3)
Liver 2 (1/482)
Lung 2 (1/482) Image Only
Mandibular process 2 (1/482) (2/3)
Maxillary process 2 (1/482) (2/3)
Midbrain 2 (1/482) (2/3)
Nose 1 (1/47) (1/1)
Oral cavity 2 (1/482) (1/3)
Skin 2 (1/482) (2/3)
Spinal cord 1 (1/46) (1/1)
Tail 2 (1/482) (1/3)
Tail somite 2 (1/482) (1/3)


Associated Images

Associated Images
  • Sleep Wake: Wake state (bmp file)
    13 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • X-ray: XRay Images Forepaw
    10 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Combined SHIRPA and Dysmorphology
    3 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • Gross Morphology Embryo E14.5-E15.5
    6 Images
  • Eye Morphology: Images Slit Lamp
    3 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Cox7ctm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Cox7ctm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre)
Vector
Gene