Gene: Ap1g1

Order

Name adaptor protein complex AP-1, gamma 1 subunit

Synonyms
  • D8Ertd374e
  • Adtg
  • gamma-adaptin

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:101919    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Ap1g1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ap1g1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal neural tube closure Ap1g1tm1b(EUCOMM)Hmgu HET Female embryonic day 9.5 0.0
embryonic growth retardation Ap1g1tm1b(EUCOMM)Hmgu HET Male embryonic day 9.5 0.0
preweaning lethality, complete penetrance Ap1g1tm1b(EUCOMM)Hmgu HOM Female Male n/a 0.0
decreased lean body mass Ap1g1tm1b(EUCOMM)Hmgu HET Female postnatal 6.59E-13
decreased bone mineral content Ap1g1tm1b(EUCOMM)Hmgu HET Female postnatal 1.94E-10
increased lean body mass Ap1g1tm1b(EUCOMM)Hmgu HET Female Male postnatal 1.7E-7
increased body length Ap1g1tm1b(EUCOMM)Hmgu HET Female Male postnatal 1.7E-6
cataract Ap1g1tm1b(EUCOMM)Hmgu HET Male postnatal 3.62E-6
abnormal behavioral response to light Ap1g1tm1b(EUCOMM)Hmgu HET Female postnatal 5.06E-6
abnormal behavior Ap1g1tm1b(EUCOMM)Hmgu HET Female Male postnatal 5.17E-6
hyperactivity Ap1g1tm1b(EUCOMM)Hmgu HET Female postnatal 1.21E-5
increased total body fat amount Ap1g1tm1b(EUCOMM)Hmgu HET Female postnatal 2.86E-5
increased bone mineral density Ap1g1tm1b(EUCOMM)Hmgu HET Female Male postnatal 3.89E-5
abnormal optic disk morphology Ap1g1tm1b(EUCOMM)Hmgu HET Female postnatal 9.72E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (2/2)
Aorta 2 No (1/562) (2/2)
Brain 2 No (6/562) (1/2)
Brainstem 2 No (4/562) (1/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562) (1/2)
Cerebellum 2 No (4/562) (1/2)
Cerebral cortex 2 No (5/562) (1/2)
Epididymis 2 No (4/106) (1/2)
Esophagus 2 No (2/393) (2/2)
Eye 2 No (1/562) (2/2)
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562) (1/2)
Hypothalamus 2 No (4/562) (1/2)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562)
Mammary gland 2 No
Midbrain 2 No (1/2)
Olfactory lobe 2 No (4/393) (2/2)
Ovary 2 No (1/562)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (1/2)
Peripheral nervous system 2 No (3/562) (1/2)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562) (1/2)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562) (1/2)
Spleen 2 No (4/562) (1/2)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562) (1/2)
Submandibular gland 2 No (1/104) (1/2)
Testis 2 No (4/562) (1/2)
Thalamus 2 No
Thymus 2 No (2/2)
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562) (1/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (2/562) (1/2)
Vascular system 2 No (1/393) (2/2)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/482)
Dorsal root ganglion 2 (1/45)
Ear 2 (1/482)
Embryo 2 (1/482) (2/2)
Eye 2 (1/482)
Foot 2 (1/482)
Forebrain 2 (1/482)
Forelimb 2 (1/482)
Fronto-nasal process 2 (1/46)
Hand 2 (1/482)
Head 2 (5/482) (2/2)
Heart 2 (1/482) (2/2)
Hindbrain 2 (6/482)
Hindlimb 2 (1/482)
Liver 2 (1/482)
Lung 2 (1/482)
Mandibular process 2 (1/482)
Maxillary process 2 (1/482)
Midbrain 2 (1/482)
Nose 2 (1/47)
Oral cavity 2 (1/482)
Skin 2 (1/482)
Spinal cord 2 (1/46)
Tail 2 (1/482) (2/2)
Tail somite 2 (1/482)


Associated Images

Associated Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • X-ray: XRay Images Forepaw
    9 Images
  • X-ray: XRay Images Dorso Ventral
    9 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    9 Images
  • X-ray: XRay Images Lateral Orientation
    9 Images
  • X-ray: XRay Images Skull Lateral Orientation
    9 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ap1g1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Ap1g1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene